Results 151 to 160 of about 39,480 (265)

Agaricus arvensis extract-coated functionalized silver nanoparticles for effective aerobic biotransformation of synthetic L-tyrosine to L-DOPA. [PDF]

AMB Express
Li Y, Ali S, Khan QF, Ahmad MU, Fatima L, Shah TA, Assefa M, Al-Emam A.   +7 more
europepmc   +1 more source

Systemic medications associate with surgically treated cataract among adults over 50 years in Finland

Acta Ophthalmologica, EarlyView.
Abstract Purpose To identify associations between systemic drugs and cataract surgery in Finland. Methods A historic cohort study based on administrative data. Endpoint event was cataract surgery. Use of drugs in question was based on redeemed prescriptions and consisted of 156 drugs.
Antti Riikonen, Jari Haukka, Tuomas Lilius, Sirpa Loukovaara   +3 more
wiley   +1 more source

Targeting hexokinase 2 to induce breast cancer cell senescence

British Journal of Pharmacology, EarlyView.
Background and Purpose Hexokinase 2 (HK2) is a key enzyme linked to high tumour cell proliferation. Its inhibitors such as 3‐bromopyruvic acid (3‐BP) induce cancer cell death, highlighting HK2 modulation as potential anti‐cancer treatment. However, standard chemotherapies often cause the emergence of senescent cancer cells, which goes along with cell ...
Helmut Bischof, Katarina Cisarova, Sandra Burgstaller, Mia Schwerer, Markus Absenger‐Novak, Philipp J. Jost, Roland Malli, Wolfgang F. Graier, Robert Lukowski   +8 more
wiley   +1 more source

Effects of Dopaminergic Therapy with Levodopa (L-DOPA) on Fear and Anxiety-Related Circuits and Symptoms in Patients with Depression and Higher Inflammation. [PDF]

Brain Behav Immun
Craig GE, Mehta ND, Bekhbat M, Revill KP, Lucido MJ, Hong C, Wommack EC, Baer WM, Haroon E, Miller AH, Li Z, Felger JC.   +11 more
europepmc   +1 more source

Characterization of dermatan sulfate and chondroitin sulfate profiles during brain regeneration in Styela plicata

The FEBS Journal, EarlyView.
Adult ascidians are capable of regenerating their entire brains following injury, and glycosaminoglycans have been shown to either promote or inhibit neuritogenesis. In this study, dermatan 2,6‐disulfate (D2,6S) was identified as the predominant complex carbohydrate in the ascidian brain.
Taynan Motta Portal, Samara de Oliveira Pimentel, Bruno da Costa Rodrigues, Mauro Sérgio Gonçalves Pavão, Rodrigo Nunes da Fonseca, Cintia Monteiro de Barros   +5 more
wiley   +1 more source

Efficient synthesis of l-DOPA in <i>Escherichia coli</i> via cofactor and enzyme engineering. [PDF]

Synth Syst Biotechnol
Deng L, Ping J, Liu Z, Linghu K, Zhang H, Shan X, Zeng W, Li J, Zhou J.   +8 more
europepmc   +1 more source

Real‐world evidence for the efficacy and tolerability of an isobutylamido‐thiazolyl‐resorcinol (Thiamidol)‐containing skincare regimen on facial hyperpigmentation and overall skin appearance: A multi‐centre study in 11 European countries

International Journal of Cosmetic Science, EarlyView.
A Thiamidol‐containing skincare regimen showed significant improvement in facial hyperpigmentation in a real‐world study across 11 European countries. The treatment led to a significant reduction in mMASI scores, enhanced overall skin condition and demonstrated high tolerability.
B. Schuster, T. Rogers, C. Vendruscolo, D. Roggenkamp, W. G. Philipp‐Dormston, F. Al‐Niaimi, S. Roussel, N. Kiss, H. Malik, D. Grozeva, K. S. Berger, C. Rauscher, L. Kolbe   +12 more
wiley   +1 more source

Preclinical Evaluation of Synthetic Biology-Driven Engineered <i>Escherichia coli</i> Nissle 1917 as a Living Therapeutic for Sustained L-DOPA Delivery. [PDF]

ACS Synth Biol
Abdalla A, Padhi P, Bakes N, Thyer R, Zenitsky G, Jin H, Anantharam V, Kanthasamy A, Ellington AD, Phillips GJ, Kanthasamy AG.   +10 more
europepmc   +1 more source

Dietary L‐Tyrosine Sustains Egg Production and Quality by Modulating Promoter CpG Methylation, Gene Expression, and Hormone Profiles in Reproductive Signalling Pathways of Aged Laying Hens

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Managing prolactin (PRL)‐mediated reproductive suppression is critical for maintaining egg production in commercial laying hens. L‐tyrosine (TYR), a precursor of dopamine (DA), may counteract age‐related reproductive decline by suppressing PRL, thereby sustaining productivity and egg quality in late‐phase laying hens.
Hasan Hüseyin İpçak
wiley   +1 more source

Reduced Cortical Pyramidal Neuron Membrane Excitability and Synaptic Function in Parkinsonian Mice and Their Restoration by L-Dopa Treatment: Indirect Mediation by Striatal Dopaminergic Activity. [PDF]

Brain Sci
Chen H, Zhong M, Lin G, Liao FF, Zhou FM.   +4 more
europepmc   +1 more source