Results 51 to 60 of about 11,284,409 (311)

Biodegradable and Biocompatible Functional Polymers for Biomedical Applications

open access: yesAdvanced Functional Materials, EarlyView.
Biodegradable and biocompatible functional polymers integrate electrical, mechanical, and stimuli‐responsive functionalities while enabling programmed degradation under physiological conditions. This review introduces recent advances in conductive, shape‐memory, self‐healing, photocurable, and adhesive polymer systems, emphasizing material design ...
Won Bae Han   +5 more
wiley   +1 more source

PET Studies of Cerebral Levodopa Metabolism: A Review of Clinical Findings and Modeling Approaches [PDF]

open access: yes, 2009
[18F]Fluoro-3,4-dihydroxyphenyl-l-alanine (FDOPA) was one of the first successful tracers for molecular imaging by positron emission tomography (PET), and has proven immensely valuable for studies of Parkinson’s disease.
Kumakura, Yoshitaka   +3 more
core   +1 more source

From Cell‐Derived Vesicles to Hybrid Nanovectors: Biological Membranes as Functional Blueprints for Gene Delivery

open access: yesAdvanced Healthcare Materials, EarlyView.
Biologically derived and hybrid nonviral nanovectors are examined as distinct but convergent design approaches. Integrating synthetic components with biologically functionalized membranes allows efficient interactions with complex cellular environments.
Clara Baldari   +10 more
wiley   +1 more source

MOESM1 of 3-O-Methyldopa inhibits astrocyte-mediated dopaminergic neuroprotective effects of l-DOPA

open access: yes, 2016
Additional file 1: Fig. S1. Levels of GDNF (A) or bFGF (B) in GCM of striatal astrocytes after the treatment with methyl-l-DOPA (25 or 50 µM) and/or 3-OMD (10 or 100 µM) for 24 h. Data are mean ± SEM (n = 6). **p 
Masato Asanuma (420841)   +1 more
core   +1 more source

Sustainable Poly(Lactic Acid)/Graphene Oxide Bioelectronic Platform for Neurotransmitters Sensing and Tunable Stimulation of Astrocytes

open access: yesAdvanced Materials, EarlyView.
This work introduces sustainable PLA/graphene oxide bioelectronic interfaces featuring electrodes with tunable conductivity and strong electrocatalytic performance. These platforms were used to implement a new method for tuning astrocyte Ca2+ signaling and for the efficient detection of key biomarkers.
Alessandra Scidà   +15 more
wiley   +1 more source

The Multimodal Serotonergic Agent Vilazodone Inhibits L-DOPA-Induced Gene Regulation in Striatal Projection Neurons and Associated Dyskinesia in an Animal Model of Parkinson’s Disease

open access: yesCells, 2020
Levodopa (L-DOPA) treatment in Parkinson’s disease is limited by the emergence of L-DOPA-induced dyskinesia. Such dyskinesia is associated with aberrant gene regulation in neurons of the striatum, which is caused by abnormal dopamine release from ...
Feras Altwal   +3 more
doaj   +1 more source

L-Dopa and the albino riddle: content of L-Dopa in the developing retina of pigmented and albino mice. [PDF]

open access: yesPLoS ONE, 2013
The absence or deficiency of melanin as in albinos, has detrimental effects on retinal development that include aberrant axonal projections from eye to brain and impaired vision. In pigmented retinal pigment epithelium (RPE), dihydroxyphenalanine (L-Dopa)
Suzanne Roffler-Tarlov   +4 more
doaj   +1 more source

Effect of Thermal Processing on Color, Phenolic Compounds, and Antioxidant Activity of Faba Bean (Vicia faba L.) Leaves and Seeds

open access: yesAntioxidants, 2021
The leaves and seeds of the faba bean are good sources of L-3,4-dihydroxyphenylalanin (L-dopa), and are usually eaten with thermal cooking methods. However, little information is available on the effect of thermal treatments on their nutritional value ...
Shu-Cheng Duan   +2 more
doaj   +1 more source

Models of probabilistic category learning in Parkinson's disease: Strategy use and the effects of L-dopa [PDF]

open access: yes, 2010
Probabilistic category learning (PCL) has become an increasingly popular paradigm to study the brain bases of learning and memory. It has been argued that PCL relies on procedural habit learning, which is impaired in Parkinson's disease (PD). However, as
Lagnado, DA   +4 more
core  

Keratin–Melanin Complexation Enables Robust, Delamination‐Resistant Feather‐Inspired Structural Color Coatings for Flexible and Curved Substrates

open access: yesAdvanced Materials Interfaces, EarlyView.
Providing mechanically robust structural color coating technology inspired by cooperative interactions in nature. The spatial arrangement of melanin particles within the keratin matrix generates angle‐independent structural colors. Diverse functional groups in keratin and melanin contribute to interparticle and substrate adhesion, resulting in the ...
Taisei Harada   +12 more
wiley   +1 more source

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