Results 231 to 240 of about 11,284,409 (311)

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

The Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor, Nycolle I. S. Souza, Bruno G. Anjos, Stephen G. Matthews, Enrrico Bloise   +4 more
wiley   +1 more source

Interplay of defects and dopants in <i>l</i>-Dopa -aided UiO-66 for superprotonic conductivity. [PDF]

RSC Adv
Selvakumar P, Somu SK, Swaminathan SV, Pal A, Nechikott AA, Nayak PK, Kundu T.   +6 more
europepmc   +1 more source

Comparative Analysis of Chemical Composition and Bioactivities of Essential Oils From Different Parts of Wild‐Grown Alpinia siamensis K.Schum. in Vietnam

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
The essential oils of Alpinia siamensis are rich in β‐bisabolene, 1,8‐cineole, and β‐pinene. These essential oils inhibit α‐amylase and tyrosinase and also suppress the growth of Escherichia coli and Bacillus subtilis. ABSTRACT This study investigated chemical composition and bioactivities of essential oils (EOs) obtained from the rhizomes (REO ...
Nguyen Thi Kim Anh, Trang H. D. Nguyen, Tran Thi Huyen, Le Nhat Tam, Dang Ngoc Phuc, Anh Tu Phan, Le Duc Giang, Duong Chi, Nguyen Thi Ngan   +8 more
wiley   +1 more source

L-Dopa-induced changes in aperiodic bursts dynamics relate to individual clinical improvement in Parkinson's disease. [PDF]

NPJ Parkinsons Dis
Agouram H, Neri M, Angiolelli M, Depannemaecker D, Bahuguna J, Schwey A, Régis J, Carron R, Malfait N, Eusebio A, Daucé E, Sorrentino P.   +11 more
europepmc   +1 more source

Moringa oleifera Lam. Seed Lectin (WSMoL) Attenuates Parkinsonian Symptoms in Mice via Anti‐Inflammatory, Antioxidant, and Neurotransmitter‐Modulating Effects

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
WSMoL attenuates motor impairment, neuroinflammation, oxidative stress, and monoamine depletion in a rotenone‐induced model of Parkinson's disease. The involvement of D1 receptor‐mediated signaling is demonstrated, providing new insights into the mechanisms underlying its neuroprotective effects and supporting WSMoL as a promising candidate for further
Leydianne Leite de Siqueira Patriota, Emanuel Davi Lima de Matos Leão, Maria Nívea Bezerra da Silva, Amanda de Oliveira Marinho, Bárbara Raíssa Ferreira de Lima, Jainaldo Alves da Costa, Luciclaudio Cassimiro de Amorim, Valéria Bianca de Souza Santos, Patrícia Maria Guedes Paiva, Michelly Cristiny Pereira, Daniella Carla Napoleão, Jorge Vinícius Fernandes Lima Cavalcanti, Leucio Duarte Vieira, Michelle Melgarejo da Rosa, Thiago Henrique Napoleão   +14 more
wiley   +1 more source

Multiple transitions to high l-DOPA 4,5-dioxygenase activity reveal molecular pathways to convergent betalain pigmentation in Caryophyllales. [PDF]

New Phytol
Walker-Hale N, Guerrero-Rubio MA, Brockington SF.   +2 more
europepmc   +1 more source

Advancing Type 1 Diabetes Treatment: 3 PM‐Oriented Innovations in Islet Transplantation and Biomaterial Engineering

Diabetes/Metabolism Research and Reviews, Volume 42, Issue 6, September 2026.
ABSTRACT Type 1 Diabetes (T1D) is an autoimmune disorder marked by the immune‐mediated destruction of pancreatic β‐cells, resulting in insulin deficiency and dysregulated glucose control. Current therapies—such as insulin replacement and artificial pancreas systems—manage symptoms but fail to restore endogenous β‐cell function or halt disease ...
Fatemeh Sabet Sarvestani, Ramin Yaghobi, Mohsen Khosravi Maharlooei, Mehdi Golshan, Mohammad Hossein Karimi   +4 more
wiley   +1 more source

Diabetic striatopathy: Hyperglycemic chorea/ballism successfully treated with L-dopa. [PDF]

J Diabetes Investig
Tsukaguchi R, Hasebe M, Shibue K, Hamasaki A.   +3 more
europepmc   +1 more source

Behavioral Phenotyping of the Pahenu2 Mouse Model for Phenylketonuria—A Scoping Review and Future Perspectives

Journal of Inherited Metabolic Disease, Volume 49, Issue 5, September 2026.
ABSTRACT Phenylketonuria (PKU) is a rare metabolic disorder resulting from a mutation in the gene encoding the enzyme phenylalanine hydroxylase (PAH), resulting in very high phenylalanine (Phe) levels in blood and brain. A PKU mutant mouse model was developed via N‐ethyl‐N‐nitrosourea (ENU) mutagenesis, mimicking the high brain Phe content seen in ...
Junfei Cao, Lennart Kruizinga, Iris B. Hovens, Els van der Goot, Robbert Havekes, Eddy A. van der Zee   +5 more
wiley   +1 more source

L-DOPA Induces Spatially Discrete Changes in Gene Expression in the Forebrain of Mice with a Progressive Loss of Dopaminergic Neurons. [PDF]

Mol Neurobiol
Radlicka-Borysewska A, Ziemiańska M, Zięba M, Szumiec Ł, Bagińska M, Chrószcz M, Gołda S, Hajto J, Korostyński M, Kreiner G, Pera J, Piechota M, Rodriguez Parkitna J.   +12 more
europepmc   +1 more source