Results 191 to 200 of about 39,513 (265)

Multiple transitions to high l-DOPA 4,5-dioxygenase activity reveal molecular pathways to convergent betalain pigmentation in Caryophyllales. [PDF]

New Phytol
Walker-Hale N, Guerrero-Rubio MA, Brockington SF.   +2 more
europepmc   +1 more source

Repurposing a Lipid Droplet‐Associated Algal Protein as a Biosensor for Phosphatidic Acid

Advanced Sensor Research, Volume 5, Issue 8, August 2026.
The DTH1 lipid binding domain (DTH1LBD) binds to lipid membranes containing phosphatidic acid (PA). Its N‐terminal amphipathic helices are sufficient for this association and, when labeled with solvatochromic fluorophores, can serve as in vitro PA biosensors.
Bilge Ercan, Nian Kee Tan, Julia Lin, Jingyao You, Stephen M. Butler, Katrina A. Jolliffe   +5 more
wiley   +1 more source

L-DOPA Induces Spatially Discrete Changes in Gene Expression in the Forebrain of Mice with a Progressive Loss of Dopaminergic Neurons. [PDF]

Mol Neurobiol
Radlicka-Borysewska A, Ziemiańska M, Zięba M, Szumiec Ł, Bagińska M, Chrószcz M, Gołda S, Hajto J, Korostyński M, Kreiner G, Pera J, Piechota M, Rodriguez Parkitna J.   +12 more
europepmc   +1 more source

mGluR5 in ECCCK to BLA Circuit Modulates Depressive‐Like Phenotypes through CCK Signaling

Advanced Science, Volume 13, Issue 43, 3 August 2026.
Dysregulation of mGluR5 and CCK signaling contributes to major depressive disorder, yet circuit‐level mechanisms remain unclear. Here, the ECCCK→BLA pathway is identified as a critical regulator of affective behavior. mGluR5 modulates synaptic function and CCK signaling within this circuit, controlling stress susceptibility and depressive‐like states ...
Muhammad Asim, Huajie Wang, Gao Qianqian, Abdul Waris, Jufang He   +4 more
wiley   +1 more source

Diabetic striatopathy: Hyperglycemic chorea/ballism successfully treated with L-dopa. [PDF]

J Diabetes Investig
Tsukaguchi R, Hasebe M, Shibue K, Hamasaki A.   +3 more
europepmc   +1 more source

Bilateral SERS‐Microneedle Patch for Co‐Diagnosis of Diabetes Mellitus and Tuberculosis Comorbidity

Advanced Science, Volume 13, Issue 45, 13 August 2026.
Our study introduced a U@mP@Au‐mediated bilateral SERS‐microneedle patch for analyzing glucose levels from ISF and sensitively detecting TB biomarkers from sputum, respectively. This integrated dual‐analyte detecting platform can be used for co‐diagnosis of diabetes mellitus (DM) and tuberculosis (TB) comorbidity, which was demonstrated in ex vivo ...
Xueqin Huang, Lingzhi Chen, Jing Xu, Jiaqi Yu, Shanze Chen, Huaihong Cai, Yanguang Cong, Pinghua Sun, Jiang Pi, Lang Rao, Jierong Chen, Junxia Zheng, Haibo Zhou   +12 more
wiley   +1 more source

Impulsive-compulsive behaviours and striatal neuroactivity in mildly parkinsonian rats under D2/3 agonist and L-DOPA treatment. [PDF]

NPJ Parkinsons Dis
Wolfschlag M, Espa E, Skovgård K, Halje P, Cenci MA.   +4 more
europepmc   +1 more source

A Supramolecular Reversible and Anisotropic Conductive Adhesive for Flexible Electronics

Advanced Science, Volume 13, Issue 45, 13 August 2026.
Supramolecular network‐based nanocomposites are developed as a stretchable conductive adhesive for flexible electronics. It's as convenient as traditional solders and constructs anisotropic conductive and robust stretchable connections among diverse soft/rigid materials.
Tongtong Li, Yahui Zhao, Ying Zhang, Yuquan Li, Xuan Ye, Hongyun Qiu, Zhaorui Zhang, Jiang‐Fei Xu, Shaobo Ji   +8 more
wiley   +1 more source

Arterial spin labeling MRI based perfusion pattern related to motor dysfunction and L-DOPA reactivity in Parkinson's disease. [PDF]

Neuroimage Clin
Zheng Q, Yuan W, Wen J, Qin J, Wu C, Wu H, Duanmu X, Tan S, Guo T, Zhou C, Wu J, Chen J, Zeng Q, Fang Y, Zhu B, Yan Y, Tian J, Zhang B, Zhang M, Guan X, Xu X.   +20 more
europepmc   +1 more source

Rational Design of π‐Conjugated Polymers for Enantioselective Recognition of Amino Acids

Advanced Electronic Materials, Volume 12, Issue 15, 10 August 2026.
A family of conducting polymers is proposed for the enantioselective recognition of amino acids. The films are generated by electropolymerization of thiophene trimers containing chiral features, with the advantage that the polymerization can be induced at much lower overpotentials compared to classic thiophene monomers, thus avoiding parasitic ...
Gerardo Salinas, Rana Nakar, Getnet Kassahun, Matthieu Raoux, Jochen Lang, Damien Thuau, Mamatimin Abbas, Eric Cloutet, Alexander Kuhn   +8 more
wiley   +1 more source