Results 241 to 250 of about 11,284,409 (311)

Cell Death in Neurodegenerative Diseases: Molecular Mechanisms and Therapeutic Targets

MedComm, Volume 7, Issue 9, September 2026.
Regulated cell death pathways, including apoptosis, necroptosis, pyroptosis, ferroptosis, and autophagy‐dependent cell death, interact with mitochondrial dysfunction, proteostasis failure, lysosomal stress, glial remodeling, and neuroinflammation across major neurodegenerative diseases.
Tianjiao Li, Qian Zhang, Yichen Wu, Ruixue Huang   +3 more
wiley   +1 more source

Impulsive-compulsive behaviours and striatal neuroactivity in mildly parkinsonian rats under D2/3 agonist and L-DOPA treatment. [PDF]

NPJ Parkinsons Dis
Wolfschlag M, Espa E, Skovgård K, Halje P, Cenci MA.   +4 more
europepmc   +1 more source

Amino Acid Metabolism in Health and Disease

MedComm, Volume 7, Issue 9, September 2026.
This graphical abstract delineates the multifaceted role of amino acid metabolism in health and disease. It illustrates how amino acids sustain physiological homeostasis across the liver, kidney, brain, heart, intestine, muscle, skeleton, and immune system.
Zhiwei Su, Jinyu Liu, Xiaoliang Deng, Yanqun Luo, Haiping Xue, Lei Wang, Lianjun Xing, Tao Wu   +7 more
wiley   +1 more source

Arterial spin labeling MRI based perfusion pattern related to motor dysfunction and L-DOPA reactivity in Parkinson's disease. [PDF]

Neuroimage Clin
Zheng Q, Yuan W, Wen J, Qin J, Wu C, Wu H, Duanmu X, Tan S, Guo T, Zhou C, Wu J, Chen J, Zeng Q, Fang Y, Zhu B, Yan Y, Tian J, Zhang B, Zhang M, Guan X, Xu X.   +20 more
europepmc   +1 more source

No Significant Secondary Structural Change of α‐Synuclein Monomer by Site‐Specific DOPA or Phosphorylation Introduction in Its C‐Terminal Region

Journal of Peptide Science, Volume 32, Issue 9, September 2026.
Site‐specifically modified α‐synuclein containing DOPA or phosphorylation was prepared by ligation of a bacterially expressed N‐terminal polypeptide and a synthetic C‐terminal modified peptide. ABSTRACT α‐Synuclein (αSyn) is a major component of pathogenic Lewy bodies and Lewy neurites and is closely associated with Parkinson's disease.
Tatsuhito Matsuo, Isao Suetake, Mariko Kimura, Satoshi Hashimoto, Koichi Matsuo, Sakiko Matsumoto, Shinji Hirotsune, Hironobu Hojo   +7 more
wiley   +1 more source

Widespread and Heterologous Effects of L-DOPA on Monoaminergic Tissue Metabolism in Newborn Rats Expressing Air-Stepping. [PDF]

Int J Mol Sci
Barrière G, Pelloquin-Mvogo Z, Boulain M, Khsime I, Bharatiya R, Riquier MA, Morin D, Allain AE, Chagraoui A, Juvin L, De Deurwaerdere P.   +10 more
europepmc   +1 more source

Elevated UV‐B alters anti‐herbivore plant defence allocation, while silicon supplementation maintains resistance

Functional Ecology, Volume 40, Issue 9, Page 2982-3000, September 2026.
Read the free Plain Language Summary for this article on the Journal blog. Abstract The impacts of elevated surface ultraviolet‐B (UV‐B) on ecological processes, such as anti‐herbivore defence in plants, remain poorly understood. Many cereal crops depend on accumulating silicon (Si) in their tissues to resist insect herbivory.
Sajjad Reyhani Haghighi, Christopher I. Cazzonelli, Sue E. Hartley, Scott N. Johnson   +3 more
wiley   +1 more source

Potential therapeutic effects of curcumin, with or without L-DOPA, on motor and cognitive functions and hippocampal changes in rotenone-treated rats. [PDF]

Metab Brain Dis
Belviranlı M, Okudan N, Sezer T.
europepmc   +1 more source

Natural Pigments and Cyclodextrins: Overview on a Synergistic Approach to Encapsulation

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 5, September 2026.
ABSTRACT The growing demand for natural dyes in the food industry has stimulated research into strategies aimed at improving their stability, solubility, and bioavailability. This review examines the synergistic use of cyclodextrins (CDs) as encapsulating agents for natural pigments, highlighting their ability to form inclusion complexes that protect ...
Chiara Pippolini, Ilaria Benucci, Claudio Lombardelli, Marco Esti   +3 more
wiley   +1 more source

Neuroprotective effect of L-DOPA-induced interleukin-13 on striatonigral degeneration in cerebral ischemia. [PDF]

Cell Death Dis
Jeon E, Seo MS, Lkhagva-Yondon E, Lim YR, Kim SW, Kang YJ, Lee JS, Lee BD, Wi R, Won SY, Chung YC, Park ES, Kim E, Jin BK, Jeon MS.   +14 more
europepmc   +1 more source