Results 211 to 220 of about 75,185 (305)

NIR‐II Imaging‐Guided Photothermal Activation of a TRPV4‐Targeted Nanoplatform Delivering Cycloastragenol to Promote Microglia Reprogramming and α‐Synuclein Clearance in Parkinson's Disease

Advanced Science, Volume 13, Issue 26, 8 May 2026.
ABSTRACT Current therapies for Parkinson's disease (PD) fail to concurrently address α‐synuclein (α‐syn) aggregation and microglia‐mediated neuroinflammation. Herein, we engineer a near‐infrared‐II (NIR‐II) phototheranostic nanoplatform, CAG/FD1080@MM‐aTRPV4, for synergistic regulation of microglial function and real‐time monitoring of PD pathology. We
Hsuan Lo, Linjuan Feng, Shiying Li, Lik Hang Hugo Tse, Xuehan Wang, Xingyang Zhao, Shaoheng Ma, Xin Li, Yanjuan Gu, Wing‐Tak Wong   +9 more
wiley   +1 more source

Molecular and cellular determinants of L-Dopa-induced dyskinesia in Parkinson's Disease. [PDF]

NPJ Parkinsons Dis
Servillo F, De Carluccio M, Di Lazzaro G, Campanelli F, Marino G, Natale G, Ledonne A, Massaro Cenere M, Paldino E, Di Giuda D, Picca A, Bove F, Di Iorio R, Angeloni B, Cimmino AT, Bellomo G, Picconi B, Bentivoglio AR, Mercuri NB, Parnetti L, Ghiglieri V, Viscomi MT, Calabresi P.   +22 more
europepmc   +1 more source

Nanomaterial‐Mediated Near‐Infrared Photothermal Neuromodulation for Neurologic Disorders

Advanced NanoBiomed Research, Volume 6, Issue 5, May 2026.
This review summarizes how near‐infrared light activates photothermal nanomaterials to enable noninvasive neuromodulation with high spatiotemporal precision. It elucidates the underlying mechanisms, explores targeted therapeutic applications for neurological disorders, discusses integration with optogenetics and biosensors, and addresses future ...
Ting‐Ting Zeng, Yu‐Ge Wang, Ya‐Bing Zhang, Yuan‐Xin Bai, Si‐Tong Lin, Ting‐Ting Zhu, Yan‐Bo Zhou, Wei‐Tong Pan, Pan‐Miao Liu, Jian‐Jun Yang   +9 more
wiley   +1 more source

Abnormal arm swing movements in Parkinson's disease: onset, progression and response to L-Dopa. [PDF]

J Neuroeng Rehabil
Patera M, Zampogna A, Pietrosanti L, Asci F, Falletti M, Pinola G, Bianchini E, Di Lazzaro G, Rosati V, Grillo P, Giannini F, Fattapposta F, Costantini G, Pisani A, Saggio G, Suppa A.   +15 more
europepmc   +1 more source

Cleaning Matters: Impact of Surface Treatment Methods on Solid‐State Nanopore Noise for High Frequency Recording

Chemistry–Methods, Volume 6, Issue 5, May 2026.
The impact of different cleaning strategies on the noise spectrum of solid state nanopores was evaluated. Noise reduction is a key challenge in solid‐state nanopore experiments, as it directly limits signal resolution and the detectability of translocation events.
Wesley Pietsch, Marc Safferthal, Niklas Geue, Artur Uzdenov, Michael Götze, Kevin Pagel   +5 more
wiley   +1 more source

L-Dopa-induced changes in aperiodic bursts dynamics relate to individual clinical improvement in Parkinson's disease. [PDF]

NPJ Parkinsons Dis
Agouram H, Neri M, Angiolelli M, Depannemaecker D, Bahuguna J, Schwey A, Régis J, Carron R, Malfait N, Eusebio A, Daucé E, Sorrentino P.   +11 more
europepmc   +1 more source

Correspondence of Basal Forebrain Resting‐State Functional Connectivity and Cerebral Glucose Metabolism Alterations With Neurotransmitter Maps in Alzheimer's Disease

CNS Neuroscience &Therapeutics, Volume 32, Issue 5, May 2026.
Altered functional connectivity of basal forebrain subregions (Ch1‐3, Ch4) and widespread cerebral hypometabolism were identified in Alzheimer's disease using simultaneous PET/MRI. Spatial correspondence with normative neurotransmitter receptor and transporter maps suggested that serotonergic and dopaminergic systems may contribute to AD‐related ...
Yujie He, Hanxiao Xue, Sheng Bi, Yan Wang, Xiaocao Liu, Yixia Li, Zhigeng Chen, Dongdong Rong, Bixiao Cui, Jie Ma, Shaozhen Yan, Jie Lu   +11 more
wiley   +1 more source

Multiple transitions to high l-DOPA 4,5-dioxygenase activity reveal molecular pathways to convergent betalain pigmentation in Caryophyllales. [PDF]

New Phytol
Walker-Hale N, Guerrero-Rubio MA, Brockington SF.   +2 more
europepmc   +1 more source

The Role of Nootropic Supplements in Sports: Enhancing Cognitive and Physical Performance Simultaneously

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
The review examines the nootropic effects of substances used in sports through their impact on neurotransmission, neuroendocrine control, energy production, synaptic plasticity, and neurovascular connections. The four key neurotransmitters dopamine, acetylcholine, serotonin, and GABA function to control motivation, attention, fatigue perception, and ...
Zheng Yi
wiley   +1 more source

Impulsive-compulsive behaviours and striatal neuroactivity in mildly parkinsonian rats under D2/3 agonist and L-DOPA treatment. [PDF]

NPJ Parkinsons Dis
Wolfschlag M, Espa E, Skovgård K, Halje P, Cenci MA.   +4 more
europepmc   +1 more source