Results 141 to 150 of about 13,238,937 (304)

Beyond Skin and Eyes: The Medical and Social Burden of Oculocutaneous Albinism in Africa: A Narrative Review

JEADV Clinical Practice, EarlyView.
ABSTRACT Oculocutaneous albinism (OCA) is a genetic disorder found worldwide, but its impact is particularly pronounced in the African continent. This results from both a higher prevalence and the persistent myths and superstitions surrounding the condition in many African communities.
Rebecca Donadoni, Niccolò Capurro, Alessandro Svizzero, Valeria Brazzelli   +3 more
wiley   +1 more source

L-Dopa and Brain Serotonin System Dysfunction

, 2015
L-dopa is used to treat the motor symptoms associated with Parkinson’s disease, a neurodegenerative movement disorder characterized by a loss of dopamine neurons.
Bryan Yamamoto, Branden J. Stansley, Branden Stansley, Bryan K. Yamamoto   +3 more
core   +1 more source

Cereal‐Legume Rotation Benefits Soil Ecosystem Multifunctionality by Improving the Efficiency of Microbial Carbon Pump

Land Degradation &Development, EarlyView.
ABSTRACT Cereal‐legume rotation is regarded as an important agricultural management strategy for enhancing soil organic carbon (SOC) and improving soil ecosystem multifunctionality (EMF). The soil microbial carbon pump (MCP) exerts a regulatory effect on the production of microbial necromass as well as the SOC accumulation.
Quanyi Hu, Yanshi Li, Jing Luo, Guangshuai Wang, Yali Zhao, Tianmin Ding, Hongen Liu, Yingxin Xie, Xuelin Zhang   +8 more
wiley   +1 more source

Levodopa is associated with reduced development of new-onset geographic atrophy in patients with age-related macular degeneration

Eye and Vision
Background Geographic atrophy (GA) is a significant cause of vision loss in patients with age-related macular degeneration (AMD). Current treatments are limited to anti-complement drugs, which have limited efficacy to delay progression with significant ...
Kyle S. Chan, Nitika Aggarwal, Shannon Lawson, Nick Boucher, Mathew W. MacCumber, Jeremy A. Lavine   +5 more
doaj   +1 more source

RETRACTION: Differential Involvement of Ras-GRF1 and Ras-GRF2 in L-DOPA-Induced Dyskinesia. [PDF]

Ann Clin Transl Neurol
RETRACTION: S. Bido, N. Solari, M. Indrigo, A. D’Antoni, R. Brambilla, M. Morari, and S. Fasano, “Differential Involvement of Ras‐GRF1 and Ras‐GRF2 in L‐DOPA‐Induced Dyskinesia,” Annals of Clinical and Translational Neurology 2, no. 6 (2015): 662–678, https://doi.org/10.1002/acn3.202. The above article, published online on 24 April 2015 in Wiley Online
europepmc   +2 more sources

Targeting the D1-N-methyl-D-aspartate receptor complex reduces L-dopa-induced dyskinesia in 6-hydroxydopamine-lesioned Parkinson’s rats

, 2016
Lu Song,1,* Zhanzhao Zhang,2,* Rongguo Hu,1 Jie Cheng,1 Lin Li,1 Qinyi Fan,1 Na Wu,1 Jing Gan,1 Mingzhu Zhou,1 Zhenguo Liu11Department of Neurology, Xinhua Hospital, 2Department of Plastic and Reconstructive Surgery, Shanghai 9th People’s Hospital,
Song L, Zhang ZZ, Zhou MZ, Hu RG, Wu N, Gan J, Liu ZG, Fan QY, Li L, Cheng J   +9 more
core  

Proteomics of Nitrotyrosine: Integrating Mass Spectrometry and Immunodetection in Redox‐Driven Pathology

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Nitrooxidative stress, driven by excess reactive nitrogen species like peroxynitrite, contributes to the pathogenesis of many chronic diseases. Among its molecular footprints, 3‐nitrotyrosine (3NT) has emerged as a biologically relevant marker of protein nitration.
Brîndușa Alina Petre
wiley   +1 more source

Functionalization of prosthetic implants with mussel-derived DOPA protein to enhance osseointegration

openIl successo clinico a lungo termine degli impianti protesici endossei dipende in larga misura dalla loro capacità di integrarsi stabilmente con il tessuto osseo circostante.
GOVONI, ESMERALDA
core  

Zeolite Membrane Bio-Reactor for L-DOPA Production

, 2010
L-DOPA is an effective drug in the treatment of Parkinson's disease, a neurological disorder which has a particular impact in elderly people. Nowadays, this drug is chemically produced (Monsanto process).
L Donato, G Clarizia, C Algieri, R Mazzei, L Giorno   +4 more
core  

Phenotypic Exploration in Patients with Heterozygous Variant in AFG3L2 Gene: A Case‐Series and Literature Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Variants in AFG3‐Like Matrix AAA Peptidase, Subunit 2 (AFG3L2) gene are associated with diverse clinical phenotypes. Here, we describe phenotypic findings of two unrelated children with de novo heterozygous variant and one family with inherited heterozygous variant in AFG3L2 gene.
Sangeetha Yoganathan, Laura Tochen, Jacky Ganguly, Sayoni Roy Chowdhury, Haya S AlFaris, Vivek Pai, Andrea LeBlanc‐Millar, Sara Breitbart, Hrishikesh Kumar, Manohar Shroff, Arun Reginald, Grace Yoon, Alfonso Fasano, George M Ibrahim, Carolina Gorodetsky   +14 more
wiley   +1 more source