Results 91 to 100 of about 13,238,937 (304)
Alpha and beta EEG power reflects L-dopa acute administration in parkinsonian patients [PDF]
, 2014 Aim: To evaluate the effect of an acute L-dopa administration on eye-closed resting state electroencephalographic (EEG) activity of cognitively preserved Parkinsonian patients.
Di Biase L +11 more
core +1 more source
Advanced Science, EarlyView.Flux‐protection engineering stabilizes an oxidation‐prone L‐DOPA node in engineered E. coli by combining acid‐adapted chassis evolution, respiratory‐chain modulation, enzyme‐level flux matching, and pH–DO control. Carbon is redirected from oxidative browning to productive biosynthesis, enabling 1075.2 mg/L curcumin and demonstrating transferability to ...
Jianbin Chen +10 more
wiley +1 more source
Severe Headbanging Responsive to Levodopa in a Child With FOXP1 Syndrome
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT We report a 9‐year‐old female with FOXP1 syndrome due to a de novo in‐frame deletion in the FOXP1 gene. The child has a severe neurodevelopmental disorder including global developmental delay and autism spectrum disorder. At age 2, she developed severe headbanging, which was progressive and did not respond to multidisciplinary, behavioral ...
Pamela Veale +2 more
wiley +1 more source
, 1993 We have established a method for measuring L-dopa in plasma and urine, including the metabolites dopamine and L-dopac, using separation by ion-pair reversed-phase HPLC and quantification with an electrochemical detector.
Copeland, L G +3 more
core +5 more sources
Neurobiology of Disease, 2008 l-3,4-dihydroxyphenylalanine (l-DOPA)-induced dyskinesia consists of involuntary choreiform and dystonic movements. Here we report whether intrastriatal l-DOPA itself is able to trigger dyskinetic behavior and which role the neurotransmitter dopamine (DA)
Kerstin Buck, Boris Ferger
doaj +1 more source
L-DOPA administration improved symptoms and motor deficits of PD marmosets.
, 2018 (A) Cumulative PDRS scores of the marmosets during the on and off L-DOPA treatments. The parkinsonian marmosets (n = 3) showed improvement in PD disabilities following L-DOPA treatment (B) Motor subscale scores showing progression of individual ...
Marcel M. Daadi (40597) +1 more
core +1 more source
The Role of Glutamatergic and Dopaminergic Genes in Resistant Schizophrenia: A Systematic Review
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.ABSTRACT Psychosis is a heterogeneous disorder, with approximately one‐third of patients experiencing treatment resistance, predominantly among individuals diagnosed with Schizophrenia. Treatment‐resistant schizophrenia (TRS) may stem from a distinct biological signature, involving abnormalities in the dopaminergic and glutamatergic systems.
Maria Teresa Moreno‐Calle +3 more
wiley +1 more source
Imbalanced Dopaminergic Transmission Mediated by Serotonergic Neurons in L-DOPA-Induced Dyskinesia
Parkinson's Disease, 2012 L-DOPA-induced dyskinesias (LIDs) are one of the main motor side effects of L-DOPA therapy in Parkinson's disease. The review will consider the biochemical evidence indicating that the serotonergic neurons are involved in the dopaminergic effects of L ...
Sylvia Navailles +1 more
doaj +1 more source
, 2016 Treatment for multiple myeloma (MM) with a combined strategy of bone and tumor targeting remains a crucial technical challenge due to the incorporation of various functional components into one single system. Here, we developed dioleoyl phosphatidic acid
Qing Chang (93814) +4 more
core +1 more source
Angewandte Chemie, EarlyView.Erneuerbare Guajacole werden durch Phenyliodid(III)diacetat rasch zu maskierten ortho‐Chinonen oxidiert und bilden eine neue Monomerklasse, die mit Multithiolen selektive Michael‐Typ‐Polyadditionen zu Polymeren mit Thiol‐Guajacol‐Verknüpfungen eingeht.
Dominik P. Hoch +7 more
wiley +1 more source