Results 161 to 170 of about 24,681,778 (305)

Clinical Characteristics of Adolescents and Youth Living With HIV Transitioning From Pediatric to Adult Clinics Before and After 18 Years in Asia. [PDF]

J Acquir Immune Defic Syndr
Lertamornkitti N, Pheerapanyawaranun C, Le ON, Nallusamy RA, Sudjaritruk T, Mohamed TJ, Puthanakit T, Ounchanum P, Kosalaraksa P, Khol V, Kumarasamy N, Qui ND, Van Nguyen L, Yusoff NKN, Kinikar A, Du QT, Fong SM, Muktiarti D, Sohn AH, Chokephaibulkit K, TREAT Asia Pediatric HIV Observational Database of IeDEA Asia-Pacific.   +20 more
europepmc   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Substituent Effects on the Stability of Pd-NHC Complexes: Switching From Molecular to "Cocktail-Type" Catalysis. [PDF]

J Comput Chem
Naumovich VO, Gordeev EG, Ananikov VP.
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Longitudinal Analysis of Physiological Adaptation in Primiparous Dairy Cows During the Transition Period. [PDF]

Vet Sci
Girdauskaitė A, Grigė S, Sabeckienė I, Džermeikaitė K, Krištolaitytė J, Japertas S, Macijauskas R, Anskienė L, Škėlaitė B, Antanaitis R.   +9 more
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Effects of Increased Ligand Fields of the Second- and Third-Row Transition Metals on the Preferred Structures of Sandwich Compounds of Stoichiometry C₁₂H₁₂M. [PDF]

Organometallics
Liu Y, Chen H, Luo J, Li H, Fan Z, Fan Q, King RB, Schaefer HF.   +7 more
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

CFAP100 forms phase-separated condensates required for ciliary transition zone assembly. [PDF]

Nat Commun
Sun S, Li K, Sun X, Tian R, Zhu LE, Liu K, Yue Y, Li W, Ran J, Zhou J, Liu M.   +10 more
europepmc   +1 more source

Gove Airport

, 1967
Gove airport, taken from the diary of L. H. Vale, lately attached to European Launcher Development Organisation (ELDO) - shows shed with cars and people waiting for plane.De La Rue, Kathy.Date ...

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