Results 51 to 60 of about 723,509 (268)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Phase transition temperatures of 405-725 K in superfluid ultra-dense hydrogen clusters on metal surfaces

AIP Advances, 2016
Ultra-dense hydrogen H(0) with its typical H-H bond distance of 2.3 pm is superfluid at room temperature as expected for quantum fluids. It also shows a Meissner effect at room temperature, which indicates that a transition point to a non-superfluid ...
Leif Holmlid, Bernhard Kotzias
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Influence of n = 1 resonant magnetic perturbation on flow and turbulence towards L-H transition

Nuclear Fusion
The application of resonant magnetic perturbation (RMP) with toroidal mode number n  = 1 on HL-3 tokamak inhibits the L-H transition at specific heating power.
Y. Zhang, M. Jiang, Z.B. Guo, P.H. Diamond, W.X. Guo, J.Q. Xu, N. Zhang, Z. Wang, Z.J. Li, Y. Zhou, A.S. Liang, T.F. Sun, R. Ke, S.B. Gong, X.X. He, W. Chen, W.L. Zhong   +16 more
doaj   +1 more source

The interplay between gastrocnemius medialis force–length and force–velocity potentials, cumulative EMG activity and energy cost at speeds above and below the walk to run transition speed

Experimental Physiology, 2023
The aim of this study was to investigate the interplay between the force–length (F–L) and force–velocity (F–V) potentials of gastrocnemius medialis (GM) muscle fascicles, the cumulative muscle activity per distance travelled (CMAPD) of the lower limb ...
Andrea Monte, Paolo Tecchio, Francesca Nardello, Beatriz Bachero‐Mena, Luca Paolo Ardigò, Paola Zamparo   +5 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Enrichment of medium-quality colostrum by adding colostrum replacer, combined or not with transition milk in the feeding of dairy calves

Scientific Reports
Fifty Holstein calves were allocated in randomized blocks and distributed in a 2 × 2 factorial arrangement; (A) two sources of Ig: (1) Control: bovine colostrum (25% Brix); (2) Enriched colostrum: mid-quality bovine colostrum (20% Brix) enriched with ...
Ana Paula Silva, Amanda M. Cezar, Ariany F. de Toledo, Marina G. Coelho, Cristiane R. Tomaluski, Gercino F. Virgínio Júnior, Carla M. M. Bittar   +6 more
doaj   +1 more source

Transition Metal (II) Coordination Chemistry Ligated by a New Coplanar Tridentate Ligand, 2,6-Bis(5-isopropyl-1H-pyrazol-3-yl)pyridine

Inorganics
Transition metal (II) complexes stabilized by 2,6-di(pyrazol-3-yl)pyridine as a novel coplanar tridentate nitrogen-donor ligand have been reported for their unusual structures and photoluminescent properties.
Kiyoshi Fujisawa, Yurika Minakawa, David James Young   +2 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source