Results 71 to 80 of about 727,385 (268)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Concurrent Treatment With Lorlatinib and Dinutuximab Beta Induced Acute Gastric Dilation in a Pediatric Patient With Neuroblastoma

Pediatric Blood &Cancer, EarlyView.
Suna Lin, Linjie Li, JiJun Chen, Zhaokun Tao, Lifeng Zhang, Junqing Mao, Jinhu Wang   +6 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Effects of Different Extraction Methods on the Composition and Properties of Jinggang Pomelo Peel Essential Oil

Shipin gongye ke-ji
Taking Jinggang pomelo peel essential oil (JPPEO) as the research object, two methods of steam distillation and low-temperature continuous phase transition were used for extraction. Orthogonal test was used to study the effects of extraction temperature,
Xin LI, Jianxin HUA, Jiehong LUO, Guoqing WANG, Gan CHEN, Aimei ZHOU   +5 more
doaj   +1 more source

Synthesis, Characterisation and Antimicrobial Evaluation of a New Bis(semicarbazone) Ligand and Its Coordination Complexes [PDF]

مجلة جامعة الانبار للعلوم الصرفة
This study aimed to synthesise a new multidentate bis(semicarbazone) ligand, (2Z,2'E)-2,2'-(((propane-1,3-diylbis(oxy))bis(2,1-phenylene))bis(methanylylidene))-bis(hydrazine-1-carboxamide) (H₂L), and to investigate its paramagnetic coordination compounds
Mohamad Hameed, Mohamad Al-Jeboori
doaj   +1 more source

Axisymmetric oscillations at L–H transitions in JET: M-mode

Nuclear Fusion, 2016
Abstract L to H transition studies at JET have revealed an n  =  0, m  =  1 magnetic oscillation starting immediately at the L to H transition (called M-mode for brevity). While the magnetic oscillation is present a weak ELM-less H-mode regime is obtained, with a clear increase of density and a weak electron temperature pedestal.
Solano, Emilia R., Vianello, N., Delabie, E., Hillesheim, J. C., Buratti, P., Réfy, D., Balboa, I., Boboc, A., Coelho, R., Sieglin, B., Silburn, S., Drewelow, P., Devaux, S., Dodt, D., Figueiredo, A., Frassinetti, L., Marsen, S., Meneses, L., Maggi, C. F., Morris, J., Gerasimov, S., Baruzzo, M., Stamp, M., Grist, D., Nunes, I., Rimini, F., Schmuck, S., Lupelli, I., Silva, C., Abhangi, M., Abreu, P., Aftanas, M., Afzal, M., Aggarwal, K. M., Aho Mantila, L., Ahonen, E., Aints, M., Airila, M., Albanese, R., Alegre, D., Alessi, E., Aleynikov, P., Alfier, A., Alkseev, A., Allan, P., Almaviva, S., Alonso, A., Alper, B., Alsworth, I., Alves, D., Ambrosino, G., Ambrosino, R., Amosov, V., Andersson, F., Andersson Sunde ́n, E., Angelone, M., Anghel, A., Anghel, M., Angioni, C., Appel, L., Apruzzese, G., Arena, P., Ariola, M., Arnichand, H., Arnoux, G., Arshad, S., Ash, A., Asp, E., Asunta, O., Cooper, D., Cooper, S. R., Corre, Y., Corrigan, G., Cortes, S., Coster, D., Couchman, A. S., Cox, M., Cox, M. P., Cox, P., Craciunescu, T., Cramp, S., Crisanti, F., Cristescu, I., Croci, G., Croft, O., Crombe, K., Crowe, R., Cruz, N., Cseh, G., Cull, K., Cupido, L., Curran, D., Curuia, M., Czarnecka, A., Czarski, T., Dalley, S., Dalziel, A., Darrow, D., Davies, R., Davis, W., Day, C., Day, I. E., de la Cal, E., de la Luna, E., De Magistris, M., de Pablos, J. L., De Tommasi, G., de Vries, P. C., Deakin, K., Deane, J., Decker, J., Degli Agostini, F., Dejarnac, R., den Harder, N., Dendy, R. O., Denner, P., Devynck, P., Di Maio, F., Di Pace, L., Dittmar, T., Donne, T., Dooley, P., Dorling, S. E., Dormido Canto, S., Doswon, S., Douai, D., Doyle, P. T., Dreischuh, T., Drozdov, V., Drozdowicz, K., Dumont, R., Dumortier, P., Atanasiu, C. V., Austin, Y., Avotina, L., Axton, M. D., Dunai, D., Dunne, M., Dˇuran, I., Durodie, F., Ayres, C., Bachmann, C., Baciero, A., Baia ̃o, D., Bailescu, V., Baiocchi, B., Baker, A., Baker, R. A., Balden, M., Balshaw, N., Bament, R., Banks, J. W., Baranov, Y. F., Barlow, I. L., Barnard, M. A., Barnes, D., Barnsley, R., Baron Wiechec, A., Basiuk, V., Bassan, M., Bastow, R., Batista, A., Batistoni, P., Bauer, R., Bauvir, B., Bazylev, B., Beal, J., Beaumont, P. S., Becoulet, A., Bednarczyk, P., Bekris, N., Beldishevski, M., Bell, K., Belli, F., Dutta, P., Duval, B., Dux, R., Dylst, K., Dzysiuk, N., Edappala, P. V., Edwards, A. M., Eich, T.h., Ekedahl, A., Elevant, T., El Jorf, R., Elsmore, C. G., Ericsson, G., Eriksson, A., Eriksson, J., Eriksson, L. G., Esposito, B., Esser, H. G., Esteve, D., Evans, G. E., Evans, J., Ewart, G. D., Ewers, D. T., Fagan, D., Falie, D., Farthing, J. W., Bieg, B., Blanco, E., Chang, C. S., Coda, S., Koskela, T., Loarte, A., Lukin, A., Makwana, R., Marchetto, C., Matejcik, S., Naulin, V., Plyusnin, V., Romanelli, F., Soare, S., Vicente, J., Wischmeier, M., FRESA, RAFFAELE   +216 more
openaire   +6 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Dimorphism of Trichosporon cutaneum and impact on its lipid production

Biotechnology for Biofuels, 2019
Background Compared to the oleaginous yeast Yarrowia lipolytica, Trichosporon cutaneum can metabolize pentose sugars more efficiently, and in the meantime is more tolerant to inhibitors, which is suitable for lipid production from lignocellulosic biomass.
Ya Wang, Riming Yan, Lijuan Tang, Libin Zhu, Du Zhu, Fengwu Bai   +5 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Determination of confinement regime boundaries via separatrix parameters on Alcator C-Mod based on a model for interchange-drift-Alfvén turbulence

Nuclear Fusion
The separatrix operational space (SepOS) model (Eich and Manz 2021 Nucl. Fusion 61 086017) is shown to predict the L–H transition, the L-mode density limit, and the ideal magnetohydrodynamic ballooning limit in terms of separatrix parameters for a wide ...
M.A. Miller, J.W. Hughes, T. Eich, G.R. Tynan, P. Manz, T. Body, D. Silvagni, O. Grover, A.E. Hubbard, A. Cavallaro, M. Wigram, A.Q. Kuang, S. Mordijck, B. LaBombard, J. Dunsmore, D. Whyte   +15 more
doaj   +1 more source