Results 171 to 180 of about 312,266 (316)

L-Lactate dehydrogenase from Cyanidioschyzon merolae shows high catalytic efficiency for pyruvate reduction and is inhibited by ATP. [PDF]

Plant Mol Biol
Yamamoto M, Osanai T, Ito S.
europepmc   +1 more source

Kinsenoside‐Loaded Microneedle Accelerates Diabetic Wound Healing by Reprogramming Macrophage Metabolism via Inhibiting IRE1α/XBP1 Signaling Axis

Advanced Science, EarlyView.
Gut metabolite trimethylamine N‐oxide accumulates in the diabetic wound area to amplify macrophage inflammation via enhancing glycolysis activities. Kinsenoside induces macrophage repolarization from M1 to M2 phenotype through inhibiting IRE1α/XBP1 pathway, followed by HIF‐1α‐glycolysis axis repression and mitophagy‐oxidative phosphorylation axis ...
Li Lu, Jiewen Liao, Chao Xu, Yuan Xiong, Juan Zhou, Guangji Wang, Ze Lin, Kangkang Zha, Chuanlu Lin, Ruiyin Zeng, Guandong Dai, Qian Feng, Bobin Mi, Guohui Liu   +13 more
wiley   +1 more source

Purification and Properties of Pyridine Nucleotide-Independent l -Lactate Dehydrogenase from Polyporus circinatus [PDF]

, 1974
S. Funayama, Glaci T. Zancan
openalex   +1 more source

Peptides inhibiting the assembly of monomeric human l-lactate dehydrogenase into catalytically active homotetramer decrease the synthesis of lactate in cultured cells. [PDF]

Protein Sci
Stefan A, Gentilucci L, Ruffolo F, Rossi V, Sordi S, He T, di Stefano G, Santino F, Brigotti M, Scotti C, Iamele L, de Jonge H, Piaz FD, Santarcangelo DR, Hochkoeppler A.   +14 more
europepmc   +1 more source

Overcoming Extreme Ammonia Inhibition on Methanogenesis by Artificially Constructing a Synergistically Community with Acidogenic Bacteria and Hydrogenotrophic Archaea

Advanced Science, EarlyView.
This study proposes a two‐step biological strategy to synergistically enhance the three stages of anaerobic digestion, ultimately eliminating the extreme ammonia inhibition and breaking through the inefficiency bottleneck of conventional biotechnology.
Heng Wu, Huaiwen Zhang, Taili Dong, Zhenyu Li, Xiaohui Guo, Heyu Chen, Yiqing Yao   +6 more
wiley   +1 more source

Structure‐Function Relationship in the Allosteric l‐Lactate Dehydrogenases from Lactobacillus casei and Lactobacillus curvatus [PDF]

, 1982
Ulrich Mayr, Reinhard Hensel, Matthias P. Deparade, Hans Pauly, Gerhard Pfleiderer, Wolfgang E. Trommer   +5 more
openalex   +1 more source

Self‐Propelled In Situ Polymerized Nanoparticles Activating the STING Pathway for Enhanced Bladder Cancer Immunotherapy

Advanced Science, EarlyView.
A self‐propelled nanomedicine delivery system forms DMCU nanoparticles in the bladder via in situ polymerization of dopamine hydrochloride, Mn2+, cGAMP, and urease. The urease‐driven propulsion enhances retention and drug delivery. These nanoparticles activate the STING pathway, stimulating dendritic cells and T cells to boost anti‐bladder cancer ...
Lei Peng, Anguo Zhao, Rongkang Li, Yujun Liu, Daitian Tang, Dashi Deng, Qi Zhuang, Rui Liang, Shaohua Zhang, Song Wu   +9 more
wiley   +1 more source

Tumor‐associated macrophages regulate the function of cytotoxic T lymphocyte through PD‐1/PD‐L1 pathway in multiple myeloma

Cancer Medicine, Volume 11, Issue 24, Page 4838-4848, December 2022., 2022
Tumor‐associated macrophages(TAMs) are a vital constituent of the tumor microenvironment and involved in the immunological escape of vicious clonal plasma cells of myeloma patients. Our research shows that CSF1R can regulates the production of TAMs while the PD‐1/PD‐L1 pathway regulates the effect of TAMs on cytotoxic T lymphocyte. It may provide a new
Jiangbo Zhang, Zhaoyun Liu, Panpan Cao, Hao Wang, Hui Liu, Luoming Hua, Hua Xue, Rong Fu   +7 more
wiley   +1 more source

Structural model Plasmodium falciparum lactate dehydrogenase ( pf L DH ) ( PDB: 1CEQ ) with NADH binding site (yellow color)

, 2013
Komal Kalani, Agarwal Jyoti, Sarfaraz Alam, Feroz Khan, Anirban Pal, Kumar Srivastava Santosh   +5 more
openalex   +1 more source

Kinetics of activation of l‐lactate dehydrogenase from Streptococcus lactis by fructose 1,6‐bisphosphate [PDF]

, 1985
Michael J. Hardman, Vaughan L. Crow, Denise S. CRUICKSHANK, G. G. PRITCHARD   +3 more
openalex   +1 more source