Results 221 to 230 of about 16,518,033 (301)

Programmable hydrodynamics of active particles. [PDF]

Nat Commun
Rohde L, Anchutkin G, Holubec V, Cichos F.   +3 more
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Isotope effect on confinement unraveled for L-mode in dimensionless scan

, 2016
Schneider P. A., Bustos A., Hennequin P., Ryter F., Bernert M., Cavedon M., Dunne M. G., Fischer R., Gorler T., Happel T., Igochine V., Kurzan B., Dermott R. M. M., Morel P., Willensdorfer M.   +14 more
openaire   +2 more sources

Equivalent Circuit Extraction of SAW Resonator with Spurious Modes Interference over a -55 °C to 85 °C Temperature Range. [PDF]

Micromachines (Basel)
Tang X, Jia Y, Gu Y.
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Experimental and Numerical Investigation of the Dynamic Characteristics of a Cracked Blisk Under Variable Operating Conditions. [PDF]

Materials (Basel)
Wang J, Chen T, Du L, Tang Z, Yu T, Yuan H, Zhang Y.   +6 more
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Graphene-nanodiamond membranes for atomic-impact sensing: design and fluorescence readout limits. [PDF]

Nanoscale Adv
Fiedler J, Eder SD, Zalieckas J.
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source