Results 231 to 240 of about 1,103,850 (332)

Impact of drying modes on preservation of essential oils in the medicinal raw material of Hyssopus officinalis L

, 2009
Aurelija Kemzūraitė, Algirdas-Jonas Raila, Egidijus Zvicevičius, Ona Ragažinskienė, Kristina Bimbiraitė‐Survilienė, Olga Kornyšova, Audrius-Sigitas Maruška   +6 more
openalex   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Fine-Tuning DiffDock-L for Allosteric Kinase Docking. [PDF]

J Chem Inf Model
Chen E, Green J, Zhang Y.
europepmc   +1 more source

Dynamic interplay of excitatory and inhibitory coupling modes of neuronal L-type calcium channels

, 2011
Petra Geier, Michael Lagler, Stefan Boehm, Helmut Kubista   +3 more
openalex   +2 more sources

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

1-MHz linewidth VCSEL enabled by monolithically integrated passive cavity for high-stability chip-scale atomic clocks. [PDF]

Light Sci Appl
Tang Z, Li C, Zhang X, Ren W, Shen K, Li C, Bai Q, Li J, Ren A, Wang H, Luo X, Xu H, Wu J.   +12 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Assessing the Stability of Metal-Organic Frameworks with Local Vibrational Mode Theory. [PDF]

J Phys Chem C Nanomater Interfaces
Trejo S, Antonio JJ, Kraka E, Chen H.
europepmc   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Non-invasive detection of metastatic papillary thyroid carcinoma after radical surgery using salivary metabolomic biomarkers. [PDF]

Arch Endocrinol Metab
Yu F, Pan J, Zhang L, Li S, Zhang C, Fu J, Zhou P, Wang J, Yao X, Ni Y, Zhang A, Meng Q, Yang R, Xu L, Wang F, Wang J, Shi L.   +16 more
europepmc   +1 more source