Results 71 to 80 of about 12,924,254 (307)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Study on the Generation of 1.9 μm Mode Superposition Conversion Laser by Double-End Off-Axis Pumping

Photonics
In this paper, the Laguerre–Gaussian (LG) mode superposition is obtained by using the technology of double-end off-axis pumping Tm:YLF crystal, and the LG mode superposition is achieved by combining the extra-cavity conversion method.
Chao Li, Xinyu Chen, Ye Sun, Jingliang Liu, Guangyong Jin   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Model of the L-Mode Confinement in Tokamaks

, 1992
Model of the L-mode confinement in tokamaks is developed based on the microscopic ballooning mode instability. The anomalous transport coefficients determine the stability below the critical beta against the ideal MHD ballooning instability.
Itoh, S.-I., Yagi, M., Ioth, K., Fukuyama, A., Azumi, M.   +4 more
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

L-Mode Confinement Model Based on Transport-MHD Theory in Tokamaks

, 1992
Theory of the L-mode confinement in tokamaks is developed based on the microscopic ballooning instability which is destabilized by the plasma transport below the critical pressure gradient against the ideal MHD instability.
Itoh, S.-I., Yagi, M., Itoh, K., Fukuyama, A., Azumi, M.   +4 more
core  

Stationarity of I-mode operation and I-mode divertor heat fluxes on the ASDEX Upgrade tokamak

Nuclear Materials and Energy, 2019
Recent I-mode investigations from the ASDEX Upgrade tokamak are reported. It is shown that neutral-beam-injection heated I-modes can be stationary, which is important in terms of extrapolability towards future fusion devices.
T. Happel, M. Griener, D. Silvagni, S.J. Freethy, P. Hennequin, F. Janky, P. Manz, D. Prisiazhniuk, F. Ryter, M. Bernert, D. Brida, T. Eich, M. Faitsch, L. Gil, L. Guimarais, A. Merle, D. Nille, J. Pinzón, B. Sieglin, U. Stroth, E. Viezzer   +20 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Change of Transport at L-and H-mode Transition

, 1990
"A new refined model of the L-mode and H-mode transition in tokamaks is presented based on the bifurcation of the radial electric field, E_r, near edge. The radial gradient of E_r is newly introduced to explain the sudden change of fluctuations as well
Itoh, K.", "Itoh, S.-I.
core  

Designing a VH-mode core/L-mode edge discharge [PDF]

, 1995
An operating mode with a very high confinement core like the VH-mode but a very low power flow to the divertor plates and low edge particle confinement like an L-mode would be beneficial.
Hinton, F.L., Staebler, G.M., Wiley, J.C.   +2 more
core   +1 more source