Results 151 to 160 of about 295,403 (308)
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
L−moment Based Regional Frequency Analysis of Annual Maximum Relative Humidity Across Pakistan
Climate change has significantly impacted regional weather patterns in Pakistan, leading to an increase in the frequency and intensity of extreme weather events, such as heatwaves, droughts, and floods.
Shahzadi, Amina
core +1 more source
Joint confidence region estimation of L-moment ratios with an extension to right censored data. [PDF]
J Appl Stat, 2013 Wang D, Hutson AD.
europepmc +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Spatially explicit regional flood frequency analysis using L-moment, GIS and geostatistical methods.
, 1998 Lacking efficient means of digital data storage and processing, previous regional flood frequency analyses seldom considered the spatial dimension of the problem explicitly.
Daviau, Jean-Luc.
core
Adaptive Hoyer-L-Moment Envelope Spectrum: A Method for Robust Demodulation of Ship-Radiated Noise in Low-SNR Environments. [PDF]
Sensors (Basel)Zhang R, Wang Q, Du S.
europepmc +1 more source
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
L-Moments Estimations for Mixture of Weibull Distributions
Journal of Data Science, 2021 Ulk¨u Eri¸so˘glu, Murat Eri¸so˘glu
openaire +1 more source