Results 121 to 130 of about 43,908 (154)

Cleaved L-selectin concentrations in meningeal leukaemia

The Lancet, 1995
Involvement of the central nervous system has important therapeutic implications in acute leukaemia. Because the identification of blast cells in cerebrospinal fluid (CSF) is often difficult, there is a need for sensitive markers of leukaemic infiltration.
Stucki A, Cordey AS, Monai N, de Flaugergues JC, Schapira M, Spertini O   +5 more
openaire   +3 more sources

Binding of L-Selectin to the Vascular Sialomucin CD34

Science, 1993
The adhesive interactions between leukocyte L-selectin and the endothelium are involved in the migration of lymphocytes through peripheral lymph nodes and of neutrophils to sites of inflammation. A recombinant L-selectin stains high endothelial venules (HEVs) in lymph nodes and recognizes sulfated carbohydrates found on two endothelial glycoproteins ...
S, Baumheter, M S, Singer, W, Henzel, S, Hemmerich, M, Renz, S D, Rosen, L A, Lasky   +6 more
openaire   +2 more sources

Identification of nucleolin as a new L-selectin ligand

Biochemical Journal, 2001
Apart from leucocyte–endothelial interactions, the adhesion molecule L-selectin mediates the homotypic adhesion of leucocytes during recruitment at sites of acute inflammation, as well as intercellular adhesion of haematopoietic progenitor cells during haematopoiesis. There is evidence that, in addition to P-selectin glycoprotein ligand-1, other as-yet-
G, Harms, R, Kraft, G, Grelle, B, Volz, J, Dernedde, R, Tauber   +5 more
openaire   +2 more sources

Rolling dynamics of a neutrophil with redistributed L-selectin

Mathematical Biosciences, 2005
The most common white blood cell is the neutrophil, which slowly rolls along the walls of blood vessels due to the coordinated formation and breakage of chemical selectin-carbohydrate bonds. We show that L-selectin receptors are rapidly redistributed to form a cap at one end of the cell membrane during rolling via selectins or chemotactic stimulation ...
King, Michael R., Sumagin, Ronen, Green, Chad E., Simon, Scott I.   +3 more
openaire   +3 more sources

Soluble L‐selectin in the connective tissue diseases

British Journal of Haematology, 1996
Plasma levels of the leucocyte adhesion molecule L‐selectin were measured by ELISA in 41 patients with rheumatoid arthritis, 18 with ankylosing spondylitis, 18 with systemic sclerosis and 27 with vasculitis together with 42 age‐ and sex‐matched controls.
A D, Blann, P A, Sanders, A, Herrick, M I, Jayson   +3 more
openaire   +2 more sources

[L-selectin expressed on peripheral monocytes and soluble L-selectin in sera in atopic diseases].

Arerugi = [Allergy], 2000
For the purpose of assessing the involvement of L-selectin in atopic diseases, we measured L-selectin expressed on peripheral monocytes and serum soluble L-selectin (sL-selectin). We enrolled 7 patients with atopic bronchial asthma(BA), 6 patients with atopic dermatitis, 12 patients with Japanese cedar pollinosis(P), and 9 healthy controls(C).
H, Yamashita, Y, Tanno
openaire   +1 more source

[Structure and function of L-selectin].

[Rinsho ketsueki] The Japanese journal of clinical hematology, 1994
L-selectin, one of the selectin (LECAM) members, is thought to be the lymphocyte homing receptor that mediates binding of lymphocytes to high endothelial venules of peripheral lymph nodes. Although L-selectin is probably the most well-characterized lymphocyte adhesion molecule, there are still a number of unresolved issues, one of which is exact ...
openaire   +1 more source

Ligands for L-Selectin: Homing, Inflammation, and Beyond

Annual Review of Immunology, 2004
Understanding the molecular basis of lymphocyte homing to lymphoid organs was originally a problem of concern only to immunologists. With the discovery of l-selectin and its ligands, interested scientists have expanded to include glycobiologists, immunopathologists, cancer biologists, and developmental biologists. Going beyond its first discovered role
openaire   +2 more sources

[Study on expression of cell surface L-selectin and soluble L-selectin in patients with acute leukemia].

Zhongguo shi yan xue ye xue za zhi, 2003
To study the relationship between the level of the soluble L-selectin (sL-selectin) in plasma and surface L-selectin expression on leukemic cells and episode and state of illness in acute leukemia patients, the plasma level of sL-selectin was measured by a sandwich enzyme-linked immunosorbent assay, and the expressions of surface L-selectin and its ...
Jian-Hua, Chang, Zhen-Hua, Qi, Fang-Ping, Chen, Qin-Zhi, Xie   +3 more
openaire   +1 more source

L-Selectin

2000
Clare M. Isacke, Michael A. Horton
openaire   +1 more source