Results 171 to 180 of about 44,172 (240)

Aging of the Hematopoietic System: Mechanisms, Consequences, and Systemic Interactions

Aging Cell, Volume 25, Issue 2, February 2026.
Hematopoietic aging arises from intrinsic stem‐cell decline and bone‐marrow niche dysfunction, leading to myeloid skewing, immunosenescence, and clonal hematopoiesis. These changes drive systemic inflammation and multi‐organ disease, which in turn further disrupt the bone‐marrow niche and hematopoietic stem cell (HSC) function, creating a vicious cycle
Masashi Miyawaki, Seiji Hashimoto, Sumito Ogawa, Yoshitaka Kase   +3 more
wiley   +1 more source

Expansion of a Novel Subset of L-Selectin⁺ Classical Monocytes in Kawasaki Disease. [PDF]

J Inflamm Res
Jin Y, Geng Z, Lin K, Gu X, Feng X, Fu S, Wang W, Xie C, Wang Y, Gong F.   +9 more
europepmc   +1 more source

Use of receptors immobilized on microspheres to identify ligand binding sites in tissue sections: detection of lymph node ligands for L-Selectin

, 1997
Xinyan Huang, R. Marks
openalex   +2 more sources

Biologics to Treat Atopic Dermatitis: Effectiveness, Safety, and Future Directions

Allergy, Volume 81, Issue 2, Page 326-344, February 2026.
ABSTRACT Atopic dermatitis (AD) is one of the most common chronic inflammatory skin diseases worldwide. The clinical presentation of AD is heterogeneous and is characterized by a relapsing and remitting course. Most patients suffer from mild AD while approximately 5% to 20% experience severe disease activity, which often requires systemic treatment ...
Marjolein S. de Bruin‐Weller, Celeste M. Boesjes, Roselie A. Achten, Lisa A. Beck, Alan D. Irvine, Christian Vestergaard, Marlies de Graaf, Femke van Wijk, Daphne S. Bakker, Stephan Weidinger   +9 more
wiley   +1 more source

Serum L-selectin levels as predictive markers for chronic major depressive disorder progression. [PDF]

Ann Gen Psychiatry
Yun Y, Mun S, Lee S, Kang HG, Lee J.
europepmc   +1 more source

Adhesion molecules in the maternal–fetal interface in healthy pregnancies and preeclampsia

Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 2, Page 298-308, February 2026.
This study revealed elevated levels of adhesion molecules in the maternal circulation and reduced levels in the fetal circulation in preeclampsia. The findings suggest systemic maternal endothelial dysfunction in preeclampsia. Lower fetal adhesion molecule levels warrant further study. Abstract Introduction Adhesion molecules are markers of endothelial
Ingrid Kverndalen Frisch, Trond Melbye Michelsen, Tove Lekva, Marie Cecilie Paasche Roland, Ane Cecilie Westerberg   +4 more
wiley   +1 more source

L-selectin mediates neutrophil rolling in inflamed venules through sialyl LewisX-dependent and -independent recognition pathways [PDF]

, 1993
UH von Andrian, JD Chambers, Ellen L. Berg, Michie Sa, DA Brown, D Karolak, Laleh Ramezani, EM Berger, KE Arfors, E C Butcher   +9 more
openalex   +1 more source

Beyond lipids: Systemic effects of lipoprotein apheresis

Transfusion, EarlyView.
Menatalla Nadim, Yamac Akgun
wiley   +1 more source

Trichostatin A Sensitizes Tumor Cells to Apoptosis Induced by Soluble Trimeric TRAIL‐Expressing Human Mesenchymal Stromal Cells

Cancer Science, Volume 117, Issue 2, Page 456-467, February 2026.
Human mesenchymal stromal cells (MSCs) were engineered to secrete an isoleucine‐zippered soluble trimeric TRAIL (SCZT) and evaluated with trichostatin A (TSA) to overcome TRAIL resistance. TSA upregulated DR5 and amplified caspase‐8–dependent apoptosis in vitro; in vivo, tumor‐homing MSCs combined with TSA suppressed the growth of both TRAIL‐sensitive ...
Ryosuke Uchibori, Ken Ohmine, Keiya Ozawa   +2 more
wiley   +1 more source

Delayed Wound Healing in the Absence of Intercellular Adhesion Molecule-1 or L-Selectin Expression [PDF]

, 2000
Tetsuya Nagaoka, Yuko Kaburagi, Yasuhito Hamaguchi, Minoru Hasegawa, Kazuhiko Takehara, Douglas A. Steeber, Thomas F. Tedder, Shinichi Sato   +7 more
openalex   +1 more source