Results 221 to 230 of about 44,172 (240)

The association of L-selectin polymorphisms with L-selectin serum levels and risk of ischemic stroke

Journal of Thrombosis and Thrombolysis, 2011
L-selectin is a member of the selectin family of cell adhesion molecules which are important in the transient attachment of leukocytes to endothelial cells, which plays a role in inflammation processes and is one of the earliest events in the pathogenesis of atherosclerosis.
Ye-Sheng, Wei, Yan, Lan, Lan-Qing, Meng, Le-Gen, Nong   +3 more
openaire   +2 more sources

Effect of uremia and hemodialysis on soluble L-selectin and leukocyte surface CD11b and L-selectin

American Journal of Kidney Diseases, 1998
Leukocyte Mac-1 (CD11b/CD18) and L-selectin (CD62L) are implicated in leukocyte adhesion to endothelial cells. In this study, L-selectin and CD11b expression on leukocytes and soluble L-selectin (sL-selectin) serum levels were investigated in 17 nondialyzed patients with chronic renal failure (CRF), in 28 chronic hemodialysis patients before ...
Dou, Laetitia, Brunet, Philippe, Dignat-George, Francoise, Sampol, J, Berland, Yvon   +4 more
openaire   +3 more sources

L‐Selectin: An Emerging Player in Chemokine Function

Microcirculation, 2003
ABSTRACTThe emigration of leukocytes across the blood‐endothelium barrier and their subsequent transmigration through the interstitium is a complex process that is vital for maintaining the efficiency of the body's innate and adaptive immunity. The chemokines, a family of low‐molecular‐weight chemoattractant cytokines, are well recognized to be key ...
Adil I, Khan, Paul, Kubes
openaire   +2 more sources

Endothelial L‐selectin ligand expression in nasal polyps

Allergy, 2009
AbstractBackground:  L‐selectins on leukocytes and their counter‐receptors on endothelial cells have been shown to be involved in leukocyte recruitment in chronic rhinosinusitis without nasal polyps (NP).Objectives:  The purpose of this study was to evaluate the expression level of functionally active endothelial L‐selectin ligands in NP obtained from ...
Ebbens, F. A., Toppila-Salmi, S. K., Renkonen, J. A., Renkonen, R. L. O., Mullol, J., van Drunen, C. M., Fokkens, W. J.   +6 more
openaire   +2 more sources

Transcriptional regulation of L-selectin (35.19)

The Journal of Immunology, 2007
Abstract L-selectin mediates tethering and rolling of lymphocytes in high endothelial venules. To study the transcriptional regulation of L-selectin, we cloned 5′-flanking sequences of the murine L-selectin gene 1084 bp upstream of the translational start site. Analysis of the 5′-flanking sequence shows no TATA box, but an Initiator-like
Xitong Dang, Nikolai A Raffler, Kenneth R Ott, Joshua Francis, Raghavendra G Mirmira, Klaus Ley   +5 more
openaire   +1 more source

The Changes of Mac-1 and L-Selectin Expression on Granulocytes and Soluble L-Selectin Level during Hemodialysis

Nephron, 1996
L-selectin and Mac-1 expressed on leukocytes are critical for leukocyte adhesion to inflamed endothelium. L-selectin is known to be rapidly shed from the cell surface of granulocytes after activation. In the present study the change of expressions of these adhesion molecules on granulocytes were analyzed by flow cytometry, and the serum concentration ...
K, Kawabata, Y, Nagake, K, Shikata, H, Makino, Z, Ota   +4 more
openaire   +2 more sources

Soluble L-selectin levels predict survival in sepsis

Intensive Care Medicine, 2002
To evaluate serum soluble L-selectin as a prognostic factor for survival in patients with sepsis.A prospective study of mortality in patients with sepsis whose serum levels of sL-selectin were measured on admission to an intensive care unit (ICU) and 4 days later.
Seidelin, Jakob B, Nielsen, Ole H, Strøm, Jens   +2 more
openaire   +3 more sources

[L-selectin expressed on peripheral monocytes and soluble L-selectin in sera in atopic diseases].

Arerugi = [Allergy], 2000
For the purpose of assessing the involvement of L-selectin in atopic diseases, we measured L-selectin expressed on peripheral monocytes and serum soluble L-selectin (sL-selectin). We enrolled 7 patients with atopic bronchial asthma(BA), 6 patients with atopic dermatitis, 12 patients with Japanese cedar pollinosis(P), and 9 healthy controls(C).
H, Yamashita, Y, Tanno
openaire   +1 more source

L-selectin

1998
Tak W. Mak, Josef Penninger, John Roder, Janet Rossant, Mary Saunders   +4 more
openaire   +1 more source

L-Selectin (CD62L) and Its Ligands

2012
Cell adhesion molecules are glycoproteins expressed on the cell surface and play an important role in inflammatory as well as neoplastic diseases. There are four main groups: the integrin family, the immunoglobulin superfamily, selectins, and cadherins. The integrin family has eight subfamilies, designated as β1 through β8.
openaire   +1 more source