Results 81 to 90 of about 56,730 (260)

Sono‐Mechanogenetics: Linking Ultrasound Physics With Cellular Mechanobiology

Advanced Science, EarlyView.
Sono‐mechanogenetics links ultrasound physics with cellular mechanotransduction to enable noninvasive control of engineered biological systems. Acoustic forces generate distinct deformation modes that activate intracellular signaling pathways, which can be coupled to synthetic gene circuits to regulate diverse cellular functions, including gene ...
Yunjia Qu, Fan Wei, Chi Woo Yoon, Qifa Zhou, Yingxiao Wang   +4 more
wiley   +1 more source

The contribution of L-selectin to airway hyperresponsiveness in chronic allergic airways disease

Journal of Asthma and Allergy, 2010
Simon G Royce, Melissa Lee, Mimi L K TangDepartment of Allergy and Immunology, Murdoch Children’s Research Institute, The Royal Children’s Hospital, Parkville, Victoria 3052, AustraliaAbstract: L-selectin is a cell adhesion molecule ...
Simon G Royce, Melissa Lee, Mimi L K Tang   +2 more
doaj  

Lselectin Levels in Patients with Endometriosis

Indonesian Journal of Obstetrics and Gynecology, 2018
Objective: To investigate the L-selectin profile in endometriotic patients. Methods: This was a cross-sectional study. Subjects were patients diagnosed endometriosis based on clinical examination, transvaginal ultrasound, MRI and CT scan at the ...
Melkiandri Fanggidae, Maria F.T. Loho, Maya E. Mewengkang   +2 more
doaj   +1 more source

Multivalent interaction and selectivities in selectin binding of functionalized gold colloids decorated with carbohydrate mimetics [PDF]

, 2011
Colloidal gold particles with functionalized organic shells were applied as novel selectin binders. The ligand shell was terminated with different monocyclic carbohydrate mimetics as simplified analogs of the sLe(x) unit found in biological selectin ...
Dekaris, Vjekoslav, Dernedde, Jens, Enders, Sven, Pfrengle, Fabian, Reissig, Hans-Ulrich, Roskamp, Meike, Schlecht, Sabine, Yekta, Shahla   +7 more
core   +1 more source

Biomimetic Bone Marrow Monocyte Membrane‐Fused Extracellular Vesicles for Targeted Therapy of Myocardial Infarction

Advanced Science, EarlyView.
This study develops a biomimetic delivery system (M‐hEV) by fusing monocyte membranes with extracellular vesicles for targeted therapy of damaged cardiac tissue. The system homes to injured myocardium through specific molecular pathways. In a myocardial infarction model, M‐hEV effectively accumulates in the heart, reduces infarct size, alleviates ...
Jiaxin Song, Hao Yang, Qiqi Zhang, Wenqin Zhou, Rui Wang, Yuxing Xie, Emeli Chatterjee, Guoping Li, Jizong Jiang, Qiulian Zhou, Cuimei Zhao   +10 more
wiley   +1 more source

Low-dose photodynamic therapy promotes vascular E-selectin expression in chest malignancies, improving immune infiltration and tumor control

Journal for ImmunoTherapy of Cancer
Background Chest malignancies such as non-small cell lung cancer (NSCLC) or pleural mesothelioma (PM) have an ominous prognosis. Photodynamic therapy (PDT) of NSCLC and PM improves patient survival, but the precise underlying mechanism remains unknown ...
Sabina Berezowska, Michel Gonzalez, Jean Yannis Perentes, Thorsten Krueger, Michel Christodoulou, Lucas Liaudet, Etienne Meylan, Tereza Losmanová, Louis-Emmanuel Chriqui, Damien Nicolas Marie, Alexandros Sifis, Christophe Gattlen, Matteo Ortolini, Yameng Hao, Olga De Souza Silva, Etienne Abdelnour-Berchtold, Ren Wang Peng, Thomas Michael Marti, Johanna Joyce, Sabrina Cavin   +19 more
doaj   +1 more source

Pathogenic PF4/Polyanion ELISA‐Negative Antibodies in HIT

American Journal of Hematology, EarlyView.
ABSTRACT Background Platelet factor 4‐polyanion enzyme‐linked immunosorbent assays (ELISAs) are considered highly sensitive for diagnosing heparin‐induced thrombocytopenia (HIT), such that current practice guidelines recommend use of ELISA‐negative results to exclude HIT.
Adam J. Kanack, Noah P. Splinter, Emily E. Mauch, Leben Tefera, Morayma Reyes Gil, Sakshi Jasra, Andrew Goodwin, Kristi J. Smock, Hadiyah Ahmad, Aneel Ashrani, Nathaniel L. Robinson, Ana I. Casanegra, Curtis G. Jones, Shannon M. Pechauer, Erin Yttre, Richard H. Aster, Mindy C. Kohlhagen, Rachel R. Leger, Gretchen Johns, David L. Murray, Lu Zhou, Demin Wang, Renren Wen, Dong Chen, Rajiv K. Pruthi, Anand Padmanabhan   +25 more
wiley   +1 more source

Elevation of serum soluble E-selectin and VCAM-1 in severe asthma

Mediators of Inflammation, 2001
Objective: To investigate the significance of circulating adhesion molecules associated with leucocyteendothelial cell interactions in asthma, serum levels of soluble E (sE)-selectin, soluble P (sP)-selectin, soluble L (sL)-selectin, and soluble vascular
Agnes Hamzaoui, Jamel Ammar, Fethi El Mekki, Olfa Borgi, Hédia Ghrairi, Mounira Ben Brahim, Kamel Hamzaoui   +6 more
doaj   +1 more source

Inhibition of Nuclear Factor of Activated T-Cells (NFAT) Suppresses Accelerated Atherosclerosis in Diabetic Mice [PDF]

, 2013
OBJECTIVE OF THE STUDY: Diabetic patients have a much more widespread and aggressive form of atherosclerosis and therefore, higher risk for myocardial infarction, peripheral vascular disease and stroke, but the molecular mechanisms leading to accelerated
Andersson, AM, Bengtsson, E, Berglund, LM, Blanco, F, Dunér, P, Garcia-Vaz, E, Gomez, MF, Nilsson, J, Spegel, P, To, F, Wigren, M, Zetterqvist, AV   +11 more
core   +1 more source

Research progress on biomarkers of traumatic brain injury

Animal Models and Experimental Medicine, EarlyView.
Traumatic brain injury: From primary insult to secondary neuroinflammation and degeneration. Abstract Traumatic brain injury (TBI) is a common disorder of the nervous system and has become a leading cause of death and disability worldwide, imposing a substantial burden on patients and their social circles. Its main symptoms include dyskinesia, language
Xuting Shen, Si Cheng, Shuyi Chen, Mengyue Wang, Tangying Li, Weicheng Xu, Yifan Zhang, Ping Yuan, Lei Shi   +8 more
wiley   +1 more source