Results 121 to 130 of about 10,565,858 (290)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Experimental Study of Sorbitol Production by Zymomonas mobilis in High Sucrose Concentration
Semina: Ciências Exatas e Tecnológicas, 2004 The sorbitol presents several industrial applications and its conventional production is of high cost and low yield. Sorbitol production by Zymomonas mobilis production has attracted attention as both production cost and environmental impact are low. The
Rui Sérgio dos Santos Ferreira da Silva +3 more
doaj
Fast computation of the exact null distribution of Spearman's rho and Page's L statistic for samples with and without ties [PDF]
, 1998 We present a new algorithm for computing the exact null distribution of the Spearman rank correlation statistic \rho, which also works in the case of ties.
Di Bucchianico, A. +4 more
core
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Calculation of the contiguity statistic.
, 2013 (A) Sample calculations of the contiguity statistic for three 18-mer shapes. (B) The contiguity statistic is strongly correlated with abundance for all lengths of RNA molecules studied; example shown is the 18-mer land-scape (r2 = 0.69 ...
Matthew C. Cowperthwaite (93322) +4 more
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Optimal estimation of the local time and the occupation time measure for an α-stable Lévy process
Modern Stochastics: Theory and ApplicationsA novel theoretical result on estimation of the local time and the occupation time measure of an α-stable Lévy process with $\alpha \in (1,2)$ is presented.
Chiara Amorino +2 more
doaj +1 more source
Research on Multi-index Statistic and Evaluation Method based on MES System
, 2015 Extracting indexes from MES system production data and make statistic and evaluation is key to make full use of it and improve its application level. A method of multi-index statistic and evaluation based on MES system for manufacturing enterprises is ...
Li X(李歆) +2 more
core
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source