Results 31 to 40 of about 14,287,062 (240)

Tryptophan transport in human fibroblast cells : a functional characterization

, 2011
There are indications that serotonergic neurotransmission is disturbed in several psychiatric disorders. One explanation may be disturbed transport of tryptophan (precursor for serotonin synthesis) across cell membranes.
Lewander, Tommy, Venizelos, Nikolaos, Lewander, Tommy,, Nikolaos Venizelos, Johansson, Jessica, Johansson, Jessica,, Jessica Johansson, Vumma, Ravi,, Vumma, Ravi, Venizelos, Nikolaos,, Ravi Vumma, Tommy Lewander   +11 more
core   +1 more source

D-, L- and D,L-Tryptophan-Based Polyamidoamino Acids: pH-Dependent Structuring and Fluorescent Properties [PDF]

, 2019
Chiral polyamidoamino acids were obtained by polyaddition of N,N’methylenebisacrylamide with D-, D,L- and L-tryptophan (M-D-Trp, M-D,L-Trp and M-L-Trp). L-tryptophan/glycine copolymers, M-G-L-Trp5, M-G-L-Trp10, M-G-L-Trp20 and M-G-L-Trp40, were prepared ...
Federica Lazzari, Daniele Marinotto, A. Manfredi, P. Ferruti, Amedea Manfredi, E. Ranucci, F. Lazzari, J. Alongi, D. Marinotto, Paolo Ferruti, Jenny Alongi, Elisabetta Ranucci, Manfredi Amedea, Ranucci Elisabetta, Lazzari Federica, Marinotto Daniele, Ferruti Paolo, Alongi Jenny   +17 more
core   +1 more source

Safety and efficacy of l‐tryptophan produced by fermentation with Escherichia coli KCCM 10534 for all animal species

EFSA Journal, 2020
Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on l‐tryptophan produced by fermentation with a non‐genetically modified strain of ...
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Vasileios Bampidis, Giovanna Azimonti, Maria de Lourdes Bastos, Henrik Christensen, Birgit Dusemund, Mojca Kos Durjava, Maryline Kouba, Marta López‐Alonso, Secundino López Puente, Francesca Marcon, Baltasar Mayo, Alena Pechová, Mariana Petkova, Yolanda Sanz, Roberto Edoardo Villa, Ruud Woutersen, Francesco Cubadda, Noël Dierick, Boet Glandorf, Lieve Herman, Alberto Mantovani, Maria Saarela, Montserrat Anguita, Elisa Pettenati, Jordi Tarrés‐Call, Fernando Ramos   +26 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Tryptophan depletion increases nausea, headache and photophobia in migraine sufferers [PDF]

, 2006
Sensitivity to light was investigated 5 and 8 h after consumption of an amino acid drink which contained L-tryptophan (balanced amino acid condition: 19 controls and 22 migraine sufferers) or which produced a short-term reduction in brain serotonin ...
Drummond, P.D.
core  

Intestinal transport of tryptophan and its derivatives

, 1964
The intestinal transport of l- and d-isomers of tryptophan and ten derivatives were studied in everted intestinal sacs of golden hamsters. It was found that l-tryptophan, 4-CH3-, 5-CH3-, and 6-CH3-dl-tryptophan, and N-chloroacetyl-l-tryptophan were ...
Linda L. Cohen, K. C. Huang
core   +1 more source

Removing the by-products acetic acid and NH4+ from the l-tryptophan broth by vacuum thin film evaporation during l-tryptophan production

Electronic Journal of Biotechnology, 2018
Background: During l-tryptophan production by Escherichia coli, the by-products, acetic acid and NH4+, accumulate in the fermentation broth, resulting in inhibited cell growth and activity and decreased l-tryptophan production.
Qingyang Xu, Fang Bai, Ning Chen, Gang Bai   +3 more
doaj   +1 more source

Safety and efficacy of l‐tryptophan produced by fermentation using Escherichia coli CGMCC 7.267 for all animal species

EFSA Journal, 2020
Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on l‐tryptophan produced by fermentation with a genetically modified strain of ...
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Vasileios Bampidis, Giovanna Azimonti, Maria de Lourdes Bastos, Henrik Christensen, Birgit Dusemund, Mojca Kos Durjava, Maryline Kouba, Marta López‐Alonso, Secundino López Puente, Francesca Marcon, Baltasar Mayo, Alena Pechová, Mariana Petkova, Yolanda Sanz, Roberto Edoardo Villa, Ruud Woutersen, Noël Dierick, Gerhard Flachowsky, Boet Glandorf, Lieve Herman, Alberto Mantovani, Maria Saarela, Robert John Wallace, Montserrat Anguita, Jordi Tarrés‐Call, Fernando Ramos   +26 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

EFFECTS OF α-METHYL-DL-TRYPTOPHAN ON THE OXIDATION OF TRYPTOPHAN

, 1955
α-Methyl-DL-tryptophan (AMT) inhibits the oxidation of DL-tryptophan by isotonic suspensions of rat liver, and the oxidation of L-tryptophan, L-tyrosine, DL-phenylalanine, and DL-methionine by cobra venom. The oxidation of L-tryptophan is accompanied by
T. L. Sourkes, Edith Townsend
core   +1 more source