Results 71 to 80 of about 14,287,062 (240)

Gene modification of the acetate biosynthesis pathway in Escherichia coli and implementation of the cell recycling technology to increase L-tryptophan production.

PLoS ONE, 2017
The implementation of a novel cell recycling technology based on a special disk centrifuge during microbial fermentation process can continuously separate the product and harmful intermediates, while maintaining the cell viability owing to the installed ...
Qingyang Xu, Fang Bai, Ning Chen, Gang Bai   +3 more
doaj   +1 more source

Multi‐Parametric Fluorescence Spectroscopy for the Detection and Characterization of Plant‐Derived Protein Residues on 316L Stainless Steel

Advanced Materials Interfaces, EarlyView.
UV–vis fluorescence spectroscopy enables sensitive monitoring of plant protein adsorption on AISI 316L stainless steel under food‐processing‐relevant conditions. Spectral deconvolution reveals adsorption‐induced changes associated with protein–surface interactions and conformational alterations, demonstrating the potential of the technique for ...
Alexander Khort, Erik Jansson, Gunilla Herting, Eva Blomberg, Kirsti Viljaste, Ahana Mukherjee, Inger Odnevall   +6 more
wiley   +1 more source

The effect of metergoline on endocrine responses to L-tryptophan.

, 2016
The effects of the 5-HT receptor antagonist, metergoline, on the prolactin and growth hormone responses to intravenous L-tryptophan were assessed in seven normal subjects.

core   +1 more source

Fermentative aminopyrrolnitrin production by metabolically engineered Corynebacterium glutamicum

Microbial Cell Factories
Aminopyrrolnitrin (APRN), a natural halogenated phenylpyrrole derivative (HPD), has strong antifungal and antiparasitic activities. Additionally, it showed 2.8-fold increased photostability compared to pyrrolnitrin, a commercially available HPD with ...
Virginia Ryandini Melati Putri, Min-Hee Jung, Ji-Young Lee, Mi-Hyang Kwak, Theavita Chatarina Mariyes, Anastasia Kerbs, Volker F. Wendisch, Hee Jeong Kong, Young-Ok Kim, Jin-Ho Lee   +9 more
doaj   +1 more source

Hydrophobic Amino Acid Tryptophan Shows Promise as a Potential Absorption Enhancer for Oral Delivery of Biopharmaceuticals

Pharmaceutics, 2018
Cell-penetrating peptides (CPPs) have great potential to efficiently deliver drug cargos across cell membranes without cytotoxicity. Cationic arginine and hydrophobic tryptophan have been reported to be key component amino acids for cellular ...
Noriyasu Kamei, Hideyuki Tamiwa, Mari Miyata, Yuta Haruna, Koyo Matsumura, Hideyuki Ogino, Serena Hirano, Kazuhiro Higashiyama, Mariko Takeda-Morishita   +8 more
doaj   +1 more source

An Anti‐Amyloidogenic Approach to Specifically Block Memory Consolidation in Mice for Therapeutic Intervention

Advanced Science, EarlyView.
Functional amyloid conversion of the translation regulator CPEB3 is essential for long‐term memory persistence. This study demonstrates that targeting this molecular switch with the anti‐amyloidogenic peptide QBP1 selectively blocks CPEB3 fibrillation without disrupting phase separation.
Paula López‐García, Kerry R. McGreevy, Maria Eugenia Vaquero, Juan M. Suarez‐Rivero, Antonio Moreno‐Rodríguez, Antonio J. Pérez‐Pulido, Daniel Ramírez de Mingo, Anna Pallé, Helena Akiko Popiel, Andrea Santi, Mario D. Cordero, José Luis Trejo, Yoshitaka Nagai, Mariano Carrión‐Vázquez   +13 more
wiley   +1 more source

Effect of 3-phenylamino-l-alanine on tryptophan binding to rat hepatic nuclear envelopes

, 1994
We have determined that the addition of 3-phenylamino-l-alanine (PAA), a recently reported contaminant in l-tryptophan implicated in the eosinophilia-myalgia syndrome, affects tryptophan binding by utilizing an in vitro measurement of 3H-tryptophan ...
Verney, Ethel, Sidransky, Herschel, Latham, Patricia S., Cosgrove, James W.   +3 more
core   +1 more source

L-tryptophan-D5

, 2017
Inelastic Neutron Scattering spectrum of L-tryptophan-D5, C₁₁H₇D₅N₂O₂, measured on the TOSCA instrument.
J. Tomkinson, ISIS
core   +2 more sources

Rab1A Promotes Hepatic Steatosis by Suppressing Mitophagy via the Raf‐1/ERK1/2/PINK1 Signaling Axis

Advanced Science, EarlyView.
Why does fat accumulate in the liver? Our study reveals Rab1A as the molecular switch that silences the cell's mitochondrial cleanup crew. Turning Rab1A off reactivates mitophagy, clears excess fat, and reverses fatty liver disease in mice—offering a promising new therapeutic target for MASLD, a growing global health challenge.
Li Zhang, Jianhua Li, Huilu Zhang, Qi Qin, Yichen Huang, Xiaofan Tian, Chao Sun, Binbin Li, Zhengxin Wang, Xin Zhang   +9 more
wiley   +1 more source

New strategy for removing acetic acid as a by-product during L-tryptophan production

Biotechnology & Biotechnological Equipment, 2019
Acetic acid, an important by-product of L-tryptophan production by Escherichia coli, is detrimental to cell growth and tryptophan accumulation. To reduce acetic acid accumulation and further improve the production of L-tryptophan, an acetyl-coenzyme A ...
Lihong Du, Zhen Zhang, Qingyang Xu, Ning Chen   +3 more
doaj   +1 more source