Results 161 to 170 of about 411,114 (243)

Fluorination augments tumor engagement and antitumor immunity of a D-peptide-based radiotheranostic agent for combinatorial immune checkpoint blockade therapy. [PDF]

J Immunother Cancer
Zhang S, Liu C, Lu Q, Liu W, Wu J, Liu J, Tong L, Zhao K, Hu Q, Chen X, Li L, Song X, Wang F, Dai D, Wang R, Hu K.   +15 more
europepmc   +1 more source

L1 syndrome [PDF]

, 2020
openaire   +1 more source

Logic‐Gated HSV‐TK/GCV Suicide Gene Circuit for Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
The BRAS comprises two modular genetic components driven by distinct tumor‐specific promoters and a failsafe layer with the NOT gate. This multi‐input logic gate circuit enables precise, specific expression of HSV‐TK in breast cancer cells with hardly expression in normal cell and effectively inhibits tumor growth in a triple‐negative breast cancer ...
Shasha Tang, Yuan Fang, Lingli Jin, Dongyang Liu, Yicheng Liu, Ruijia Zheng, Liyun Yong, Xin Wu, Longliang Qiao, Meiyan Wang, Fengfeng Cai   +10 more
wiley   +1 more source

Myeloid-derived PD-L1 characterizes spatially organized immune architecture in colorectal cancer. [PDF]

Front Immunol
Wu Q, Tissot S, Peddle A, Yin K, Sagaert X, De Hertogh G, Abdelkader B, Pu T, Van Herpe F, D'Hoore A, Rusakiewicz S, Verbandt S, Tejpar S, Rasschaert G.   +13 more
europepmc   +1 more source

Amodiaquine Enhances Anti‐Melanoma Efficacy of Attenuated Salmonella via Targeting Glutathione Reductase in Neutrophils

Advanced Science, EarlyView.
This study shows that Salmonella VNP20009 recruits pro‐tumor neutrophils that reduce its anticancer efficacy. Combining VNP with amodiaquine selectively eliminates these neutrophils by targeting glutathione reductase. A GR‐shRNA‐loaded VNP strain was further developed, demonstrating an innovative strategy integrating drug repurposing with synthetic ...
Wanfa Dong, Chunyuan Zhao, Chengxi Li, Lin Weng, Zehan Ji, Peiqi Li, Jiqiang Lu, Danni Liu, Anni Yu, Tianyi Jiang, Shaokai Huang, Heng Liu, Xiao Chen, Zichun Hua   +13 more
wiley   +1 more source

Immunotherapy in triple-negative breast cancer: mechanisms of resistance and emerging approaches: a narrative review. [PDF]

J Yeungnam Med Sci
Koh SA.
europepmc   +1 more source

Protein L1 [PDF]

, 2019
openaire   +1 more source

Liposomal Nanoconfinement Enables Type I Photodynamic Conversion for Synergistic Cancer Photothermal‐Immunotherapy

Advanced Science, EarlyView.
Liposomal nanoconfinement converts the hemicyanine photosensitizer RhM from Type‐II to Type‐I photodynamic therapy (PDT) while enhancing photothermal therapy (PTT). The RhM‐R837@Lip nanoassembly efficiently generates superoxide (O2•−) and hydroxyl radicals (•OH) to kill tumor cells and achieve tumor ablation.
Minglu Zhang, Shanshan Liang, Meng Wang, Tingfeng Zhang, Jinke Liu, Yuyuan Peng, Hao Fang, Lingna Zheng, Xiao He, Meng Wang, Luling Wu, Tony D. James, Wei Zhao, Bing Wang, Weiyue Feng   +14 more
wiley   +1 more source

Prognostic significance of programmed death-ligand 1 expression in betel nut chewing patients with oral squamous cell carcinoma. [PDF]

BMC Oral Health
Yang HZ, Kung LY, Lin YC, Yang CY, Lin GJ, Chen YW, Ye RH, Chang WC.   +7 more
europepmc   +1 more source