Results 31 to 40 of about 396,211 (234)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Working memory capacity, noticing, and L2 speech production [PDF]

open access: yes, 2007
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Comunicação e Expressão. Programa de Pós-Graduação em Letras/Inglês e Literatura CorrespondenteO presente estudo investigou a relação entre a capacidade de memória de trabalho, o ...
Bergsleithner, Joara Martin
core  

The Teachers’ Roles in Reducing the Interference of L1 in Audio-lingual Classrooms: A Qualitative Case Study in Malaysian Primary School

open access: yesREiLA, 2021
This research article explores the teachers’ roles in reducing L1 (First Language) interference in audio-lingual classrooms. The main concern of the audio-lingual method is to focus less on grammar and teaching it inductively.
Mohammad Naim Rahim   +1 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Optionality in L2 grammars: the acquisition of SV/VS contrast in Spanish [PDF]

open access: yes, 2008
This study examines the L2 acquisition of word order variation in Spanish by three groups of L1 English learners in an instructed setting. The three groups represent learners at three different L2 proficiencies: beginners, intermediate and advanced.
Domínguez, Laura, Arche, María J.
core   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Motivation and Lexical Availability in Chilean Students Learning English as L2

open access: yesGlocality
The following study describes motivation and lexical availability in Chilean university students learning English as a second language (L2). A non-experimental, cross-sectional analysis was conducted with 136 English pedagogy students from San Sebastián ...
Sergio Moreno-Jorquera   +2 more
doaj   +1 more source

Teaching strategies in language classes

open access: yesИбероамериканские тетради, 2015
Because of the diversity in the classroom, the teacher should develop a series of strategies that allow you to transmit knowledge effectively. Teaching is difficult, even more, in second language classroom, where in addition to the student´s individual ...
M. del M. Palenzuela Pérez   +1 more
doaj   +1 more source

ALFABETIZZAZIONE DI ADULTI IMMIGRATI: LE DONNE BURKINABÉ A SPILIMBERGO

open access: yesLe Simplegadi, 2020
Language courses for immigrant women have recently attracted the interest of scholars. A number of cases are cited by literature and studied from both a linguistic and socioeconomic point of view.
Gianluca Baldo
doaj   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

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