Results 11 to 20 of about 153 (90)

RPL26 (ribosomal protein L26) [PDF]

open access: bronzeAtlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Review on RPL26 (ribosomal protein L26), with data on DNA, on the protein encoded, and where the gene is implicated.
Kristy Boggs, Michael B. Kastan
openalex   +4 more sources

Regulation of p53 Translation and Induction after DNA Damage by Ribosomal Protein L26 and Nucleolin [PDF]

open access: bronzeCell, 2005
Increases in p53 protein levels after DNA damage have largely been attributed to an increase in the half-life of p53 protein. Here we demonstrate that increased translation of p53 mRNA is also a critical step in the induction of p53 protein in irradiated cells. Ribosomal protein L26 (RPL26) and nucleolin were found to bind to the 5' untranslated region
Masatoshi Takagi   +3 more
  +8 more sources

Mdm2 Regulates p53 mRNA Translation through Inhibitory Interactions with Ribosomal Protein L26 [PDF]

open access: bronzeMolecular Cell, 2008
Mdm2 regulates the p53 tumor suppressor by promoting its proteasome-mediated degradation. Mdm2 and p53 engage in an autoregulatory feedback loop that maintains low p53 activity in nonstressed cells. We now report that Mdm2 regulates p53 levels also by targeting ribosomal protein L26. L26 binds p53 mRNA and augments its translation.
Yaara Ofir-Rosenfeld   +4 more
openalex   +5 more sources

Negative regulation of HDM2 to attenuate p53 degradation by ribosomal protein L26 [PDF]

open access: greenNucleic Acids Research, 2010
HDM2 is a p53-specific E3 ubiquitin ligase. Its overexpression leads to excessive inactivation of tumor protein p53, diminishing its tumor suppressor function. HDM2 also affects the cell cycle, apoptosis and tumorigenesis through interacting with other molecules, including several ribosomal proteins.
Yong Zhang   +10 more
openalex   +5 more sources

Saccharomyces cerevisiae Ribosomal Protein L26 Is Not Essential for Ribosome Assembly and Function [PDF]

open access: bronzeMolecular and Cellular Biology, 2012
Ribosomal proteins play important roles in ribosome biogenesis and function. Here, we study the evolutionarily conserved L26 in Saccharomyces cerevisiae, which assembles into pre-60S ribosomal particles in the nucle(ol)us. Yeast L26 is one of the many ribosomal proteins encoded by two functional genes.
Reyes Babiano   +3 more
openalex   +5 more sources

Interactions of Nucleolin and Ribosomal Protein L26 (RPL26) in Translational Control of Human p53 mRNA [PDF]

open access: greenJournal of Biological Chemistry, 2012
Ribosomal protein RPL26 enhances p53 translation after DNA damage, and this regulation depends upon interactions between the 5'- and 3'-UTRs of human p53 mRNA (Takagi, M., Absalon, M. J., McLure, K. G., and Kastan, M. B. (2005) Cell 123, 49-63; Chen, J., and Kastan, M. B. (2010) Genes Dev. 24, 2146-2156).
Jing Chen, Kexiao Guo, Michael B. Kastan
openalex   +4 more sources

Optimization of horizontal well fracturing mode in Gaotaizi tight reservoirs of L26 well block in Daqing Oilfield [PDF]

open access: goldIOP Conference Series: Earth and Environmental Science, 2021
Abstract The tight reservoir of the Gaotaizi oil layer in the L26 well area of Daqing Oilfield is a typical sand sheet deposit, with complex geological conditions. It is difficult to evaluate the production of horizontal wells in tight reservoirs with different well layout and fracturing operation scales, and the reasonable fracturing ...
Lifeng Liu   +3 more
openalex   +3 more sources

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