Results 11 to 20 of about 194,085 (156)

Species variation in the cartilaginous endplate of the lumbar intervertebral disc. [PDF]

open access: yesJOR Spine, 2022
Species variation in the CEP of lumbar IVDs was determined based on histology and SEM analysis. The integration of BEP‐CEP in humans, pigs, goats, and rabbits was mainly achieved by the collagen bundles anchoring system, while the typical BEP‐CEP interface did not exist in rats.
Li YH   +8 more
europepmc   +2 more sources

Design and Characterization of a Novel eEF2K Degrader with Potent Therapeutic Efficacy Against Triple-Negative Breast Cancer. [PDF]

open access: yesAdv Sci (Weinh)
Dysregulated eukaryotic elongation factor 2 kinase (eEF2K) expression is implicated in the pathogenesis of triple‐negative breast cancer (TNBC). Compound C1 is designed and synthesized, which shows potent activity in degrading eEF2K protein. C1 significantly inhibits the proliferation and metastasis of TNBC.
Zhong C   +12 more
europepmc   +2 more sources

Towards Platinum(II) Complexes for in cellulo Applications: Synthesis, Characterization, Biological and Catalytic Evaluation

open access: yesHelvetica Chimica Acta, Volume 106, Issue 8, August 2023., 2023
Abstract With the aim of achieving bioorthogonal intracellular catalysis, a library of platinum(II) complexes was synthesized. Their non‐toxicity to living cells was demonstrated and their catalytic activity was evaluated on a cyclization reaction leading to a highly fluorescent coumarin. None of the platinum complexes showed any catalytic activity for
Lisa Gourdon‐Grünewaldt   +6 more
wiley   +1 more source

Synthesis of Geminal Bis‐ and Tetrakisphosphonate Ester Derivatives and Their Coordination Behavior Towards Ca(II) Ions

open access: yesEuropean Journal of Inorganic Chemistry, Volume 2022, Issue 17, June 17, 2022., 2022
Geminal Bisphosphonate (BP) Esters in Ca(II) Ion Coordination. A series of geminal BPs was prepared starting from their corresponding ethyl‐ or isopropyl (arylmethylene)phosphonate ester precursors. Complexation with CaCl2 yields the derived coordination compounds [Ca(H2O)2(L1–L3)2]Cl2 or [Ca(L8)Cl2]n.
Ingo Koehne, Rudolf Pietschnig
wiley   +1 more source

Mathematical Modelling of the Spatial Epidemiology of COVID‐19 with Different Diffusion Coefficients

open access: yesInternational Journal of Differential Equations, Volume 2022, Issue 1, 2022., 2022
This paper addresses the discrepancy between model findings and field data obtained and how it is minimized using the binning smoothing techniques: means, medians, and boundaries. Employing both the quantitative and the qualitative methods to examine the complex pattern involved in COVID‐19 transmission dynamics reveals model variation and provides a ...
Benedict Barnes   +7 more
wiley   +1 more source

Context Evaluation in the Implementation of the Inclusive Education Program at SDN 20 Mataram and SDN 42 Mataram, Indonesia [PDF]

open access: yes, 2023
This research examines implementing inclusive education programs in elementary schools in Mataram City. This research aims to determine the objectives and foundations for implementing the Inclusive Education program at SDN 20 Mataram and SDN 42 Mataram ...
Asrin, Asrin   +4 more
core   +5 more sources

Influence of Career Satisfaction on Teachers’ Attrition and Retention in Public Secondary Schools of Dass Local Government Area in Bauchi State, North Eastern-Nigeria [PDF]

open access: yes, 2021
The disregard of teachers' needs had an influence negatively on our educational system in Nigeria. This study was undertaken to explore the influence of career satisfaction on teachers' attrition and retention in public secondary schools of Dass Local ...
Maigari, Martha Adamu   +3 more
core   +2 more sources

A Phenomenological Study on the Feelings, Challenges, and Difficulties Experienced by Information Technology Students in Learning Computer Programming [PDF]

open access: yes, 2022
This study aims to identify the experiences of information technology (IT) students in learning computer programming. Specifically, the feelings towards learning programming and the challenges and difficulties encountered by IT students were determined ...
Olipas, Cris Norman
core   +2 more sources

Literacy Promotion Among Members of the National Union of Road Transport Workers in Ibadan Metropolis, Nigeria [PDF]

open access: yes, 2023
This study addressed the electoral violence perpetrated by particular National Union of Road Transport Workers members, also known as „The Union‟. The prevailing perception is that the entire group is associated with street urchins and thugs who unleash ...
Akinyemi, Yusuf Akinola
core   +2 more sources

Community Economic Empowerment Management in Sukarara Village, West Sakra District, East Lombok District, Indonesia [PDF]

open access: yes
This research describes how community economic empowerment is managed in Sukarara village, West Sakra subdistrict, East Lombok district. This research uses qualitative research with a case study method using data from interviews, observations and ...
Fahruddin, Fahruddin   +4 more
core   +4 more sources

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