Results 61 to 70 of about 34,367,900 (254)

Futuro porvenir. Ensayos sobre la actitud psicoanalítica en la clínica de la niñez y adolescencia

open access: yesNatureza Humana - Revista Internacional de Filosofia e Psicanálise
    
openaire   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Influência do fenômeno La Niña na precipitação pluvial na Região Oeste de Santa Catarina

open access: yesAgropecuária Catarinense, 2020
Dados de estações hidrológicas e de temperatura da superfície do mar (TSM) foram utilizados com o objetivo de avaliar o comportamento da precipitação pluvial no Oeste de Santa Catarina durante alguns anos do fenômeno La Niña.
Gilsânia de Souza Cruz   +1 more
doaj  

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

La niña Eva Evans /

open access: yes, 1952
La niña Eva ...

core  

La Niña Modoki impacts Australia autumn rainfall variability

open access: yes, 2009
[1] Both El Niño-Southern Oscillation (ENSO) and ENSO Modoki affect Australian rainfall but the commonalities and contrasts of their impacts have not been fully explored.
Cai, W., Cowan, T.
core   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

La niña Dora Figueroa

open access: yes, 2019
La niña Dora ...

core  

Kemi - La Niña de la Semila

open access: yes, 2019
Kemi es una niña del pueblo matsigenka de Madre de Dios. Su nombre significa "niña agradable". Cumple seis años y su abuelito Rupi le tiene una gran sorpresa.
Servicio Nacional Forestal y de Fauna Silvestre
core   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

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