Laboratory animal anesthesia classification (LAAC) [PDF]
Abstract Anesthesia and analgesia (AA) are major components of animal research. However, various studies have shown an undesirable quality of AA reporting and use in research proposals and even high impact articles. Part of the problem may be related to a lack of special training in animal anesthesia among researchers. This causes an absence of
Siavash Ahmadi‐Noorbakhsh
openalex +2 more sources
DAPT Is Comparable to OAC Following LAAC With WATCHMAN FLX [PDF]
Left atrial appendage occlusion (LAAO) is an approved alternative for stroke prevention in atrial fibrillation for patients with an "appropriate rationale" to avoid long-term oral anticoagulation (OAC). Many patients undergoing LAAO are at high risk of bleeding.This study sought to investigate whether dual antiplatelet therapy (DAPT) is a safe ...
Megan Coylewright +10 more
+5 more sources
Indications and Outcome in Patients Undergoing Left Atrial Appendage Closure—The Austrian LAAC Registry [PDF]
Background: Complete real-world data on the indications and outcomes of left atrial appendage closure (LAAC) outside of clinical trials are rare. In this study, we stratified patients undergoing LAAC by indication groups. Methods: This analysis of the national multicentre Austrian LAAC Registry comprised all patients that underwent LAAC up until 2018 ...
David Zweiker +23 more
openalex +4 more sources
Size matters - body size and acute device-implantation failure after LAAC [PDF]
Abstract Funding Acknowledgements Type of funding sources: None. Introduction Patient-device mismatch in patients undergoing left atrial appendage closure (LAAC) may lead to failure to implant, dislocation, and cardiac tamponade ...
David Zweiker +14 more
openalex +2 more sources
Clinical outcomes of Watchman vs. Amplatzer occluders for left atrial appendage closure (WATCH at LAAC) [PDF]
Abstract Aims This study compares clinical outcomes of Watchman vs. Amplatzer devices for left atrial appendage closure (LAAC). Methods and results Of two real-world registries, the Watchman registry Lichtenfels, Germany, and the ...
Caroline Kleinecke +13 more
openalex +5 more sources
What characterizes device‐related thrombosis following LAAC, if ejection fraction fails to shine? [PDF]
AbstractCardiac compartmental size depends on sex, with smaller values found in (healthy) women compared to a matched group of men. Various types of heart disease may cause dilation of the affected chamber. For example, atrial fibrillation (AF) is associated with enlarged left atrial (LA) size, often also implying increased left ventricular (LV) size ...
Peter L. M. Kerkhof +2 more
openalex +5 more sources
Cardioembolic Breakthrough Stroke: When Anticoagulation Fails, Is Left Atrial Appendage Closure the Next Step? [PDF]
European Journal of Neurology, Volume 32, Issue 10, October 2025.
Palaiodimou L, Tsivgoulis G.
europepmc +2 more sources
Percutaneous Left Atrial Appendage Closure in Patients With Cardioembolic Breakthrough Stroke: An International Observational Study. [PDF]
Main Results of the Study. ABSTRACT Background Patients with non‐valvular atrial fibrillation (AF) who experience an ischemic stroke despite oral anticoagulation (OAC) are at particularly high risk of recurrence, with a reported annualized ischemic stroke rate of 5.3%–8.9%. The optimal strategy for secondary prevention in these patients remains unknown.
Galea R +15 more
europepmc +2 more sources
Neoadjuvant chemoradiation therapy (CRT) in locally advanced adenocarcinomas (laac) of the oesophago-gastric junction [PDF]
M. Stahl +9 more
openalex +2 more sources
Background: Atrial fibrillation has been identified as an independent risk factor for thromboembolic events. Since 1948 different surgical techniques have described the feasibility and the rationale of left atrial surgical appendage closure.
Mizar D'Abramo +12 more
doaj +1 more source

