Results 31 to 40 of about 274 (87)

A Combined Model‐Based Meta‐Analysis of Aggregated and Individual FEV1 Data From Randomized COPD Trials

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 2, February 2026.
ABSTRACT Model‐based meta‐analysis allows integration of aggregated‐level data (AD) from different clinical trials in one model to assess population efficacy/safety. However, AD is limited in individual‐level information, while individual‐patient‐level data (IPD) are hard to obtain. Combined modeling may take advantage of both sources.
Liang Yang, Carolina Llanos‐Paez, Shuying Yang, Claire Ambery, Alienor Berges, Maria C. Kjellsson, Mats O. Karlsson   +6 more
wiley   +1 more source

Comparison of oral anticoagulation and antiplatelet therapy during the midperiod after percutaneous left atrial appendage closure

Frontiers in Cardiovascular Medicine
Background and aimThere is a lack of evidence comparing anticoagulation and antiplatelet therapy during the midperiod time after left atrial appendage closure (LAAC) in clinical practice (the “early period” is defined as “45 days” after LAAC for a single
Chang-Yi Li, Lu Zhou, Jing-Rui Zhang, Li-Hong Huang, Li-Zhu Guo, Song-Nan Li, Cai-Hua Sang, De-Yong Long, Jian-Zeng Dong   +8 more
doaj   +1 more source

Impact of conscious sedation and general anesthesia on periprocedural outcomes in Watchman left atrial appendage closure

Cardiology Journal, 2021
BACKGROUND: Transcatheter left atrial appendage closure (LAAC) is performed either in conscious sedation (CS) or general anesthesia (GA), and limited data exist regarding clinical outcomes for the two approaches.
Caroline Kleinecke, Wasim Allakkis, Eric Buffle, Xiao-Xia Liu, Yamen Mohrez, Steffen Gloekler, Johannes Brachmann, Steffen Schnupp, Stephan Achenbach, Jiangtao Yu   +9 more
doaj   +1 more source

Efficacy of pharmacological and non‐pharmacological interventions for pre‐operative anxiety: a systematic review with network meta‐analysis of randomised clinical trials

Anaesthesia Reports, Volume 14, Issue 1, January‐June 2026.
Summary Pre‐operative anxiety is distressing for patients and is associated with peri‐operative complications, yet the relative effectiveness of available pharmacological and non‐pharmacological interventions remains unclear. We conducted a systematic review with network meta‐analysis to compare anxiolytic strategies in the pre‐operative setting.
G. M. Pinto, E. E. T. Belfort, A. V. M. de Sousa, L. A. A. C. Silva, C. C. de Carvalho   +4 more
wiley   +1 more source

On Emerging British‐Latinx Art: The Case of Art Ubicua

Bulletin of Latin American Research, Volume 45, Issue 1, January 2026.
ABSTRACT The historicisation of Latinx art has been consolidated as a field of study in the United States. While categorising art by specific communities or geographic regions can sometimes marginalise artists, such classifications have also opened up opportunities in spaces that might otherwise remain exclusive and inaccessible.
Clara Garavelli
wiley   +1 more source

Real‐World Antithrombotic Management of Nonvalvular Atrial Fibrillation in Patients Undergoing Percutaneous Coronary Intervention in China: A Cross‐Sectional Study

Cardiovascular Therapeutics, Volume 2026, Issue 1, 2026.
Antithrombotic therapy in patients with nonvalvular atrial fibrillation (NVAF) undergoing percutaneous coronary intervention (PCI) is clinically challenging, with real‐world strategies often remaining inconsistent. This study analyzed 2020 annual data from the Shanghai Cardiac Intervention Quality Control Center, encompassing 23,115 patients who ...
Jiwei Yu, Shuolin Liu, Run Du, Qinglan Tao, Jinzhou Zhu, Fenghua Ding, Ruiyan Zhang, Zhengbin Zhu, Jiang-Shan Tan   +8 more
wiley   +1 more source

Impact of Pulsed‐Field Ablation on the Left Atrial Appendage Diameter—Insights From Intra‐Procedural Echocardiography

Journal of Cardiovascular Electrophysiology, Volume 36, Issue 12, Page 3149-3155, December 2025.
Impact of pulsed‐field ablation on the left atrial appendage diameter ABSTRACT Introduction Concomitant pulmonary vein isolation (PVI) and left atrial appendage (LAA) occlusion (LAAO) have become frequently used therapies. Pulsed‐field ablation (PFA), will likely be used for combined PVI plus LAAO procedures.
Nándor Szegedi, Piotr Gardziejczyk, Zoltán Salló, Gábor Orbán, Márton Boga, Paweł Szymkiewicz, Marta Skowrońska, Patrik Tóth, Ferenc Komlósi, Béla Merkely, Ewa Wlazłowska‐Struzik, László Gellér, Jakub Baran, Dhiraj Gupta   +13 more
wiley   +1 more source

Comparing Effectiveness and Safety of Left Atrial Appendage Closure Devices: A Network Meta‐Analysis of Randomized Controlled Trials

Clinical Cardiology, Volume 48, Issue 11, November 2025.
In this network meta‐analysis of randomized controlled trials comparing Watchman, Amplatzer Amulet, and/or anticoagulation, we found evidence that Amulet was associated with significantly greater risk of pericardial effusion than Watchman (RR = 2.12). Safety and effectiveness of these devices were otherwise comparatively similar.
John W. Davis, Steven L. Mai, Wissam Harmouch, Jenna Reisler, Micaela MacKay, Elizabeth Davis, Pavel Osmancik, Michael W. Rich   +7 more
wiley   +1 more source

Impact of Immunosuppressive Drugs on Patients With Percutaneous Left Atrial Appendage Occlusion

Journal of Cardiovascular Electrophysiology, Volume 36, Issue 11, Page 2979-2989, November 2025.
ABSTRACT Introduction Percutaneous left atrial appendage closure (LAAC) reduces the risk of thromboembolic stroke in patients with non‐valvular atrial fibrillation who cannot tolerate long‐term oral anticoagulation. However, outcomes after LAAC in patients requiring chronic immunosuppressive therapy (IMS) remain unknown. This study aimed to investigate
Daisuke Togashi, Christopher R. Ellis, Zachary T. Yoneda, Jackon G. Gregory, Shunsuke Uetake, Salah H. Alahwany, Michael T. Baker, Arvindh N. Kanagasundram   +7 more
wiley   +1 more source

Systematic review and meta-analysis of left atrial appendage closure's influence on early and long-term mortality and strokeCentral MessagePerspective

JTCVS Open
Objective: Left atrial appendage closure (LAAC) concomitant to heart surgery in patients with underlying atrial fibrillation (AF) has gained attention because of long-term reduction of thromboembolic complications. As of mortality benefits in the setting
Mariusz Kowalewski, MD, PhD, Michał Święczkowski, MD, Łukasz Kuźma, MD, PhD, Bart Maesen, MD, PhD, Emil Julian Dąbrowski, MD, Matteo Matteucci, MD, Jakub Batko, MD, PhD, Radosław Litwinowicz, MD, PhD, Adam Kowalówka, MD, PhD, Wojciech Wańha, MD, PhD, Federica Jiritano, MD, PhD, Giuseppe Maria Raffa, MD, PhD, Pietro Giorgio Malvindi, MD, PhD, Luigi Pannone, MD, Paolo Meani, MD, PhD, Roberto Lorusso, MD, PhD, Richard Whitlock, MD, PhD, Mark La Meir, MD, PhD, Carlo de Asmundis, MD, PhD, James Cox, MD, PhD, Piotr Suwalski, MD, PhD   +20 more
doaj   +1 more source