Results 11 to 20 of about 2,246 (191)
Clinical significance of gastrointestinal bleeding history in patients who undergo left atrial appendage closure [PDF]
Background and Aim: Anticoagulant users with nonvalvular atrial fibrillation (NVAF) sometimes suffer from gastrointestinal bleeding (GIB) and have difficulty continuing the medication.
Inoo, Shoko +15 more
core +3 more sources
Antithrombotic Therapy after Percutaneous Left Atrial Appendage Closure: Evidence, Challenges and Future Directions. [PDF]
Percutaneous left atrial appendage closure (LAAC) has been established in clinical practice as an attractive alternative to oral anticoagulation for preventing stroke in patients with atrial fibrillation and high bleeding risk.
Galea, Roberto, Räber, Lorenz
core +5 more sources
The Future of LAAC—In 5, 10, and 20 Years
Early experience with percutaneous LAA closure documented complication rates of ∼10%, with failure to implant devices in ∼10% of patients. These numbers are unrecognizable in contemporary practice due to the iterative changes made largely in the last 10 years.
Daniels, Matthew J +1 more
core +7 more sources
Background Percutaneous left atrial appendage closure (LAAC) has been suggested as an alternative to long‐term oral anticoagulation for nonvalvular atrial fibrillation, but comparative data remain scarce. We aimed to assess ischemic and bleeding outcomes
Angelo Oliva +15 more
core +2 more sources
Background Patients with atrial fibrillation (AF) who are not suitable for long‐term anticoagulant therapy undergo percutaneous left atrial appendage closure (LAAC).
Shunsuke Kubo +6 more
core +2 more sources
Aim. The feasibility and safety of performing the combined procedure of catheter ablation (CA) and left atrial appendage closure (LAAC) for atrial fibrillation (AF) have been reported by observational studies without controls.
Peng-Pai Zhang +8 more
core +2 more sources
Incomplete endothelialization (IDE) of left atrial appendage closure (LAAC) devices increases the risk of device-related thrombosis (DRT) and stroke. Insulin resistance (IR) may contribute to IDE by impairing endothelial function, but its role remains unclear.
Jing Zhou +7 more
openaire +4 more sources
Efficacy and safety of concomitant left atrial appendage closure and pulmonary vein isolation compared to left atrial appendage closure only - A meta-analysis. [PDF]
Background: Atrial fibrillation (AF) is associated with an increased risk of ischemic stroke, primarily originating from the left atrial appendage (LAA).
Rattka I +8 more
europepmc +2 more sources
Left Atrial Appendage Closure vs. Oral Anticoagulation in Patients With Atrial Fibrillation: An Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials. [PDF]
Efficacy and safety outcomes from meta‐analysis of left atrial appendage closure versus anticoagulation therapy in atrial fibrillation. Pooled analysis of 3116 participants from four randomized trials demonstrated comparable composite outcome of stroke, systemic embolism, and cardiovascular/unexplained mortality between LAAC and standard ...
Chilaka C +12 more
europepmc +2 more sources
Background: Atrial fibrillation has been identified as an independent risk factor for thromboembolic events. Since 1948 different surgical techniques have described the feasibility and the rationale of left atrial surgical appendage closure.
Mizar D'Abramo +12 more
doaj +1 more source

