Results 21 to 30 of about 4,427 (209)

A broad-spectrum pneumococcal vaccine induces mucosal immunity and protects against lethal Streptococcus pneumoniae challenge

Emerging Microbes and Infections, 2023
Pneumococcal disease is a major threat to public health globally, impacting individuals across all age groups, particularly infants and elderly individuals.
Fang-Feng Chiu, Ling-Ling Tu, Wangxue Chen, Hongyan Zhou, Bing-Sin Liu, Shih-Jen Liu, Chih-Hsiang Leng   +6 more
doaj   +1 more source

Percutaneous left atrial appendage occlusion: putting the most lethal human attachment behind bars [PDF]

, 2012
Hospital Israelita Albert EinsteinUniversidade Federal de São Paulo (UNIFESP) Escola Paulista de MedicinaCardiovascular Research FoundationUNIFESP ...
Caixeta, Adriano, Généreux, Philippe, Silva, Erlon O. De Abreu   +2 more
core   +3 more sources

Combined Therapy of Catheter Ablation and Left Atrial Appendage Closure for Patients with Atrial Fibrillation: A Case-Control Study

Journal of Interventional Cardiology, 2020
Aim. The feasibility and safety of performing the combined procedure of catheter ablation (CA) and left atrial appendage closure (LAAC) for atrial fibrillation (AF) have been reported by observational studies without controls.
Bin-Feng Mo, Jian Sun, Peng-Pai Zhang, Wei Li, Mu Chen, Jia-Li Yuan, Yi Yu, Qun-Shan Wang, Yi-Gang Li   +8 more
doaj   +1 more source

Percutaneous Left Atrial Appendage Closure in Patients With Cardioembolic Breakthrough Stroke: An International Observational Study. [PDF]

Eur J Neurol
Main Results of the Study. ABSTRACT Background Patients with non‐valvular atrial fibrillation (AF) who experience an ischemic stroke despite oral anticoagulation (OAC) are at particularly high risk of recurrence, with a reported annualized ischemic stroke rate of 5.3%–8.9%. The optimal strategy for secondary prevention in these patients remains unknown.
Galea R, Casu G, Bini T, Laconi A, Merella PL, Chalkou K, Preda A, Cerciello M, D'Angelo G, Bella PD, Mazzone P, Auer E, Gasys A, Seiffge DJ, Fischer U, Räber L.   +15 more
europepmc   +2 more sources

COST-MINIMIZATION OF VILANTEROL / UMECLIDINIUM VERSUS OLODATEROL / TIOTROPIUM IN THE BASIC THERAPY OF SEVERE AND VERY SEVERE COPD

Фармакоэкономика, 2017
The recently introduced novel drug combinations for the treatment of COPD are based on long-acting beta-agonists (vilantererol / umeclidinum bromide) and long-acting anticholinergics (olodaterol / tiotropium bromide).
E. G. Kosolapov, F. S. Kochenkov, N. L. Pogudina, D. V. Blinov, N. L. Bondarenko, A. V. Karaulov   +5 more
doaj   +1 more source

Left Atrial Appendage Closure Yields Favorable Cardio- and Cerebrovascular Outcomes in Patients With Non-valvular Atrial Fibrillation and Prior Stroke

Frontiers in Neurology, 2022
Introduction: Patients with non-valvular atrial fibrillation (NVAF) and previous stroke are at significantly higher risk of stroke recurrence. Data on the efficacy of left atrial appendage closure (LAAC) on these patients is limited.
Mingzhong Zhao, Mingzhong Zhao, Mengxi Zhao, Cody R. Hou, Felix Post, Nora Herold, Jens Walsleben, Zhaohui Meng, Zhaohui Meng, Jiangtao Yu, Jiangtao Yu   +10 more
doaj   +1 more source

COST-EFFECTIVENESS OF VILANEROL / UMECLIDINIUM VERSUS TIOTROPIUM IN SEVERE AND VERY SEVERE COPD

Фармакоэкономика, 2017
In accordance with currently accepted recommendations for the diagnosis and treatment of chronic obstructive pulmonary disease (COPD), both monotherapy with long-acting anticholinergics (LAAC) or combined therapy (LAAC / long-acting beta-agonists, LABA ...
E. G. Kosolapov, F. S. Kochenkov, N. L. Pogudina, D. V. Blinov   +3 more
doaj   +1 more source

DNA methylation governs the dynamic regulation of inflammation by apoptotic cells during efferocytosis [PDF]

, 2017
Efficient clearance of apoptotic cells (AC) is pivotal in preventing autoimmunity and is a potent immunosuppressive stimulus. However, activation of cells prior to apoptosis abolishes their immunoregulatory properties.
Brown, MA, Ehrenstein, MR, Jordan, CK, McGovern, JL, Notley, CA   +4 more
core   +1 more source

Laboratory animal anesthesia classification (LAAC)

, 2022
Abstract Anesthesia and analgesia (AA) are major components of animal research. However, various studies have shown an undesirable quality of AA reporting and use in research proposals and even high impact articles. Part of the problem may be related to a lack of special training in animal anesthesia among researchers. This causes an absence of
openaire   +1 more source

Left Atrial Appendage Closure for Atrial Fibrillation in the Elderly >75 Years Old: A Meta-Analysis of Observational Studies

Diagnostics, 2022
Background: Left atrial appendage closure (LAAC) is an established therapy for patients with atrial fibrillation (AF); however, there is a limited understanding of LAAC in elderly patients (≥75 years old).
Shaojie Han, Ruikun Jia, Shenyu Zhao, Juan Chan, Yixuan Bai, Kaijun Cui   +5 more
doaj   +1 more source