The transcriptional adapter ADA2 interacts with the histone acetyltransferase GCN5 to regulate starch and storage protein content in wheat grains through histone acetylation. ADA2 undergoes phase separation and is modulated by GCN5, affecting histone acetyltransferase activity and gene transcription.
Xiaobang Zhang +15 more
wiley +1 more source
Decentralized clinical trials: A comprehensive analysis of trends, technologies, and global challenges. [PDF]
Kijewski S +4 more
europepmc +1 more source
Two optimized TadA‐derived base editors efficiently generate diverse splicing variants by targeting specific splice sites in potato. ABSTRACT Pre‐messenger RNA (pre‐mRNA) splicing is a critical mechanism for post‐transcriptional regulation in plants. Through alternative splicing, plants produce diverse transcriptomes and proteomes that finely regulate ...
Kaiyuan Chen +8 more
wiley +1 more source
Considerations on the implementation of DCT: a SCAT-based analysis of fact-finding interviews in Europe and the United States, with implications for regions newly adopting DCT, including Japan. [PDF]
Taruno H +5 more
europepmc +1 more source
CO2‐sensitive K+ channel traffic affects stomata and whole‐plant water use
CO2‐responsive regulation of membrane trafficking influences the density of the potassium ion (K+) channel KAT1 at the plasma membrane. CO2‐sensitive traffic, dependent on trafficking by the SNARE SYP121, impacts stomatal gas exchange and plant growth.
Zhiyi Yu +4 more
wiley +1 more source
Visceral Peritoneum Hyperpigmentation in Chickens Is Associated with <i>DCT</i> Expression. [PDF]
Dong X +7 more
europepmc +1 more source
Heterogeneity of miRNAs in Salivary Gland Neoplasms: An Exploratory Pilot Study
ABSTRACT Introduction MicroRNAs (miRNAs) are small RNAs that have been associated with tumourigenesis and tumour progression and that play an important role in the pathogenesis of salivary gland neoplasms. The aim of this study was to evaluate the global miRNA expression profile in a sample of salivary gland neoplasms.
Dandara Andrade de Santana +11 more
wiley +1 more source
Assessing reporting completeness and characteristics in decentralized randomized controlled trials: a scoping review protocol. [PDF]
Wang J +6 more
europepmc +1 more source
Cellular pool of aromatic amino acid aminotransferase proteins represented as holo‐ or apo‐ enzymes, reflecting presence or absence of associated PLP. Status of PLPHP is implicated in determining the ratio of holo‐ and apo‐TyrB. ABSTRACT Pyridoxal 5′‐phosphate (PLP) is an essential cofactor required for metabolic functions including amino acid ...
Brandi A. Buckner, Diana M. Downs
wiley +1 more source
Selecting and Preparing Clinical Sites for the Successful Conduct of Decentralized Clinical Trial Activities-Findings From the Trials@Home RADIAL Proof-of-Concept Trial. [PDF]
Lipinska K +12 more
europepmc +1 more source

