Results 181 to 190 of about 9,724 (224)

Isoflurane aggravates pre-existing proteotoxicity in adult nematodes by suppressing mitochondrial fitness. [PDF]

Sci Rep
Elami T, Zhu H, Bruck-Haimson R, Srivastava V, Zaretsky A, Cohen I, Gross E, Cohen E.   +7 more
europepmc   +1 more source

CDK7 as a Potential Exploratory Biomarker for Distinguishing Acute Myocardial Infarction Subtypes via DDR Pathways: Evidence From a Bangladeshi Cohort

Clinical Cardiology, Volume 49, Issue 6, June 2026.
Differential expression of DNA damage response genes was evaluated in Bangladeshi AMI patients. CDK7 showed significantly higher expression in NSTEMI compared to STEMI, while ATM, OGG1, and NBN showed no subtype‐specific differences, highlighting potential transcriptional heterogeneity between AMI subtypes.
Rifat Hossain Ripon, Hasnat Zahin, Abdullah Al Noman, Abdullah Al Saba, Mohammad Sayem, A.H.M. Nurun Nabi, Tahirah Yasmin   +6 more
wiley   +1 more source

Taking three-dimensional x-ray diffraction (3DXRD) from the synchrotron to the laboratory scale. [PDF]

Nat Commun
Oh S, Jin Y, Lee S, Li W, Geauvreau K, Williams M, Drake R, Bucsek A.   +7 more
europepmc   +1 more source

Effect of C5a Receptor Antagonist on the Osteogenic Differentiation of Dental Pulp Stem Cells

Clinical and Experimental Dental Research, Volume 12, Issue 3, June 2026.
ABSTRACT Objective Complement component 5a (C5a) binding to its receptor (C5aR) can mediate pro‐inflammatory immune responses, which impairs osteogenic differentiation of dental pulp stem cells (DPSCs). The present study aimed to evaluate the regulatory effect of C5aR antagonist (W54011) on the osteogenic differentiation of DPSCs in an in vitro ...
Xiaohan Tan, Junlong Hu, Junhui Li, Zhuangying Chen, Xin Shi, Jie Liu, Mingyue Liu, Weiping Hu   +7 more
wiley   +1 more source

Convolutional neural network and wavelet composite against geometric attacks a watermarking approach. [PDF]

Sci Rep
Lakshmi C, Nithya C, Sivaraman R, Sridevi A, Santhiyadevi R, Ravichandran D, Banu SA, Mahalingam H, Meikandan PV, Amirtharajan R.   +9 more
europepmc   +1 more source

Characterization of Harderian Gland‐Derived Plasma Cells in Chicken

European Journal of Immunology, Volume 56, Issue 6, June 2026.
An isolation protocol for plasma cells (PC) from the chicken Harderian gland (HG) was established, and analyses of PCs revealed a FSChigh/CD45med/sIgpos/CD57pos/CXCR4high/TACIlow phenotype. Presence of CXCL12 and BAFF around HG PCs suggests a contribution of CXCL12–CXCR4 and BAFF–TACI to PC localization and survival.
D. von La Roche, I. Naumann, E. Szőcs, V. Halasy, M. Kohn, B. Kaspers, N. Nagy, S. Härtle   +7 more
wiley   +1 more source

Acute myeloid leukaemia cells express high levels of androgen receptor but do not depend on androgen signaling for survival. [PDF]

Leukemia
Miraki-Moud F, Ariza-McNaughton L, KoKo T, Othman J, Stronge R, de Bono J, Russell N, Thomas I, Gilkes A, Burnett A, Santiago LR, Cafferty F, Taussig L, Thornhill A, O'Connor S, Bonnet D, Taussig DC.   +16 more
europepmc   +1 more source

A Hybrid Deep Learning Approach With Multimodal Neurocognitive Features and Quantum Optimization for Early Detection of Alzheimer's Disease and Related Dementias

Engineering Reports, Volume 8, Issue 6, June 2026.
A hybrid deep learning framework integrating convolutional–transformer networks and global gated attention is proposed for early dementia detection using multimodal MRI and speech data. Quantum marine predator optimization enhances classification performance, achieving superior accuracy and robustness compared with existing state‐of‐the‐art methods ...
R. Anandan, V. S. Shaisundaram, A. Abirami, Saravanakumar Sengottaiyan   +3 more
wiley   +1 more source

Characterization of Ets-1 deficiency-induced depigmentation in a mouse model: insights into vitiligo pathogenesis. [PDF]

Lab Anim Res
Chang WY, Tai TS, Lin YC, Chen PH, Chang CY, Su YC, Kao YH.   +6 more
europepmc   +1 more source

RXR Gamma Enables Oligodendrocyte Differentiation by Suppressing Sonic Hedgehog Signaling

Glia, Volume 74, Issue 6, June 2026.
Using pharmacogenetic approaches, Baldassarro et al. demonstrate that RXRγ suppresses the SHH signaling pathway in OPCs to ensure their efficient differentiation following T3 stimulation. Accordingly, Rxrg−/− OPCs displayed compromised differentiation which was normalized by the pharmacological inhibition of the hyperactive SHH pathway.
Vito Antonio Baldassarro, Quentin Brassart, Valérie Fraulob, Laura Calzà, Wojciech Krezel   +4 more
wiley   +1 more source