Results 161 to 170 of about 9,724 (224)

An implementation science study of a campus-based drug checking service at a Canadian university. [PDF]

PLoS One
Airth L, Wallace B, Kennedy MC, Standing L, Marcheterre A, Ti L, Matthews J, Feddersen M, Oelke ND.   +8 more
europepmc   +1 more source

Single versus repeated intravenous oncolytic reovirus infusions: Implications for immune modulation and rationalised scheduling of therapy in hepatocellular carcinoma

International Journal of Cancer, Volume 158, Issue 12, Page 3252-3267, 15 June 2026.
What's new? Oncolytic viruses are a promising immunotherapeutic approach against many malignancies. However, it is unclear whether repeated doses have improved therapeutic value or may trigger greater side effects, especially in patients with hepatocellular carcinoma whose liver is chronically damaged.
Karen J. Scott, Emma J. West, Rebecca J. Brownlie, Fay Ismail, Christy Ralph, Thomas Heineman, Matt Coffey, Alan A. Melcher, Alison Taylor, Salvatore Papa, Adel Samson   +10 more
wiley   +1 more source

Salidroside Selectively Binds to SEC23A and Ameliorates Psychological Stress-Induced Hyperpigmentation. [PDF]

Pharmaceuticals (Basel)
Yang M, Sun X, Wang D, Nie H, Cheng K, Gu J, Chen L, Zhang Y, Yang L, Katayama I, Li Y, Wu H.   +11 more
europepmc   +1 more source

Compartment‐Specific Immune Remodeling of Renal Aging With C1q‐Associated Podocyte Activation

The FASEB Journal, Volume 40, Issue 11, 15 June 2026.
Aging repatterns the renal immune response in a compartment‐specific manner, distinct from chronic kidney disease (CKD) adaptation. Glomerular aging features C1q‐associated podocyte activation and macrophage engagement, whereas tubulointerstitial aging is marked by B‐cell aggregation and tertiary lymphoid structure expansion.
Ju‐Young Moon, Kyuwon Shim, Hyun Ji Lim, Dae‐Kyu Kim, Young Yoon Moon, Su‐Woong Jung, Yang‐Gyun Kim, Hyuno Kang, Tae‐Hoon Lee, Jae‐Hyung Lee, Sang‐Ho Lee   +10 more
wiley   +1 more source

miR-133a-3p and miR-338-3p shape neural crest derivatives in zebrafish. [PDF]

Life Sci Alliance
Steeman TJ, Torres M, Weiner AM, Rubiolo JA, Sánchez LE, Coux G, Calcaterra NB.   +6 more
europepmc   +1 more source

miRNA Sensor HuR Compartmentalizes Ago2‐Uncoupled miRNAs to Lipid Droplets to Buffer miRNA Activity in Mammalian Cells

The FASEB Journal, Volume 40, Issue 11, 15 June 2026.
This study revealed a dose‐dependent miRNA buffering mechanism involving extracellular export and storage of miRNA on lipid droplets. The protein HuR facilitates miRNA buffering by dissociating miRNAs from Ago2 and promoting miRNA accumulation on lipid droplets or its extracellular export, depending on cellular requirements.
Sreemoyee Chakraborty, Diptankar Bandyopadhyay, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +3 more
wiley   +1 more source

Forward-model-based grain reconstruction to improve the tolerance of diffraction contrast tomography for increased sample deformation. [PDF]

J Appl Crystallogr
Fang H, Ludwig W.
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, Volume 16, Issue 6, Page 1115-1131, June 2026.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Detail-preserving denoising of CT and MRI images via adaptive clustering and non-local means algorithm. [PDF]

Sci Rep
Sharma M, Dogra A, Goyal B, Gupta A, Saikia MJ.   +4 more
europepmc   +1 more source

Piezoelectric Surface Charge and Dynamic Stimulation Synergize to Promote Cardiac Myoblast Alignment and Maturation

Advanced Healthcare Materials, Volume 15, Issue 22, 12 June 2026.
Surface polarization of PVDF films combined with mechanical stimulation generates piezoelectric electrical cues that modulate cardiomyoblast behaviour. Non‐poled and poled PVDF substrates provide distinct electroactive microenvironments influencing cell adhesion, proliferation, and differentiation.
Rafaela M Meira, Sylvie Ribeiro, Senentxu Lanceros‐Mendez, Clarisse Ribeiro   +3 more
wiley   +1 more source