Results 171 to 180 of about 9,724 (224)

Evaluating statistical consistency for the ocean component of earth system models using physics informed convolutional autoencoder. [PDF]

Sci Rep
Yu Y, Zhang S, Fu H, Chen D, Jin Y, Gao Y, Lin X, Liu Z, Lv X, Fei Y, Wang K.   +10 more
europepmc   +1 more source

ELABELA Targets Mitochondria to Modulate Heart Development

Advanced Science, Volume 13, Issue 33, 15 June 2026.
The role of peptide ELABELA (ELA) in cardiomyocyte apoptosis and congenital heart disease (CHD) is unclear. ELA deficiency caused cardiomyocyte apoptosis and CHD. A novel ELA‐APJ‐AKT‐BCL2/BAX axis in regulating mitochondrial function and contributing to CHD pathogenesis was established.
Jian Wang, Qingjie Wang, Zhikang Xu, Shuang Zhou, Yue Zhou, Junjie Yang, Lingfeng Tong, Zhuo Meng, Mei Yang, Wen Zhao, Tie Yang, Hualin Wang, Jun Zhang, Rubin Tan, Lei Wang, Yuqiang Huang, Bin Zhou, Sun Chen, Bing Zhang, Jinxiang Yuan, Jianyuan Zhao, Alex F. Chen, Kun Sun   +22 more
wiley   +1 more source

An in vitro study on the antimicrobial efficacy of a calcium hydroxide versus a calcium silicate-based endodontic medicament. [PDF]

Clin Oral Investig
Jana D, Dzinovic E, Almaroof A, Mehta D, Elsharkawy S, Deb S, Niazi S.   +6 more
europepmc   +1 more source

DMAP1 Deficiency Suppresses Lung Cancer Progression by Destabilizing Replication Fork and Activating IFN Signaling‐Mediated Anti‐tumor Immunity

Advanced Science, Volume 13, Issue 33, 15 June 2026.
Lung cancer remains the leading cause of cancer‐related death. We investigated the role of the epigenetic regulator DMAP1 in NSCLC and found that its loss induces replication stress and DNA damage. This in turn activates type I IFN signaling via the cGAS–STING pathway and transcriptional ISG de‐repression, enhancing anti‐tumor immune responses ...
Kan Huang, Xi Dai, Shuaihu Li, Yingxue Chen, Yaxin Yu, Lin Wang, Kun Liu, Shuhan Lyu, Chongyang Li, Yihua Sun, Fei Li   +10 more
wiley   +1 more source

Digital cultural intelligence and its role in enhancing expatriate work adjustment: A configurational approach in global work environments. [PDF]

PLoS One
Mahdy F, Binzafrah F, Elsawy O.
europepmc   +1 more source

Rejuvenated Amorphous Alloys: Processing Methods, Microstructures and Mechanical Properties

Advanced Science, Volume 13, Issue 33, 15 June 2026.
Three rejuvenation methods – mechanical and thermal rejuvenation, and other rejuvenation routes such as ultrasonic processing – can be used to modify structures of glassy alloys, especially atomic clusters, and therefore enhances plasticity and activates work‐hardening behaviors.
Can Yang, Yu Chen, Chunguang Tang, Si Lan, Jun Tan, Heng Ye, Hua Chen, Zhifu Yao, Jürgen Eckert, Dongxian Zhang, Jian‐Zhong Jiang   +10 more
wiley   +1 more source

MERS-CoV and SARS-CoV-2 infection in diverse human lung organoid-derived cultures. [PDF]

J Virol
Chiok KL, Jenik K, Fenton M, Falzarano D, Dhar N, Banerjee A.   +5 more
europepmc   +1 more source

Optimized Deep Learning Framework for Diabetic Retinopathy Based on Systematic Multi‐Stage Transfer Learning and Predictive Risk Stratification

Applied AI Letters, Volume 7, Issue 2, June 2026.
A multi‐stage transfer learning framework systematically optimizes CNN architectures for diabetic retinopathy detection and risk stratification from fundus images. EfficientNetB7 achieves 96% accuracy while a survival‐inspired model generates continuous risk scores aligned with DR severity for clinically meaningful patient risk assessment.
Mujidat Jibrin, Abdsamad Benkrid
wiley   +1 more source

Inactivation of Histone Chaperone HIRA Unmasks a Link Between Normal Embryonic Development of Melanoblasts and Maintenance of Adult Melanocyte Stem Cells. [PDF]

Aging Cell
Jaber-Hijazi F, Arnold R, Swaminathan K, Gilroy K, Wenzel AT, Lagnado A, Kirschner K, Robertson N, Reid C, Fullarton N, Pawlikowski J, Rai TS, Baranyk I, Shi CH, Yip KY, Blyth K, Mesirov JP, Harris ML, Passos JF, Machesky LM, Adams PD.   +20 more
europepmc   +1 more source

LncRNA MIR503HG serves as a diagnostic biomarker in patients with sepsis and regulates sepsis‐induced inflammation and cardiac dysfunction

Journal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
MIR503HG was downregulated in sepsis and sepsis‐induced cardiac dysfunction (SICD) and served as a diagnostic biomarker. Overexpression of MIR503HG attenuated myocardial injury and systemic inflammation in a septic rat model. Mechanistically, MIR503HG acted as a ceRNA by sponging miR‐497‐5p to upregulate BDNF, revealing a protective MIR503HG/miR‐497‐5p/
Pingping Qi, Minghe Jiang, Minsheng Wu, Shengkui Chen, Qile Ye, Rong Tang   +5 more
wiley   +1 more source