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Lab-on-a-chip or Chip-in-a-lab: Challenges of Commercialization Lost in Translation
Procedia Technology, 2015 Lab-on-a-chip technology has been long envisaged to have tremendous commercial potential, owing to the ability of such devices to encapsulate a full range of laboratory processes in a single instrument and operate in a portable manner, rapidly and at low
Ian Gibson, Mazher Iqbal Mohammed
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2003
Summary:In the past ten years there has been a rapid growth of the research and application area known as Lab-on-a-Chip. After an initial focus on electrokinetic separation techniques on chip, the scope of the field has widened to include topics like microfluidics, DNA analysis, cell analysis, microreactors and mass spectrometer interfacing. As well as
Oosterbroek, R.E., van den Berg, A.
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Summary:In the past ten years there has been a rapid growth of the research and application area known as Lab-on-a-Chip. After an initial focus on electrokinetic separation techniques on chip, the scope of the field has widened to include topics like microfluidics, DNA analysis, cell analysis, microreactors and mass spectrometer interfacing. As well as
Oosterbroek, R.E., van den Berg, A.
openaire +3 more sources
A quantum mechanics lab on a chip
Lab on a Chip, 2010Chip technology has evolved from the desire to further shrink the size of semiconductor devices. The high sensitivity of the electronic properties of nanostructured semiconductors can be used to detect humidity, temperature, magnetic fields and other fundamental quantities.
Ensslin K +4 more
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Nanomaterials and lab-on-a-chip technologies
Lab on a Chip, 2012Lab-on-a-chip (LOC) platforms have become important tools for sample analysis and treatment with interest for DNA, protein and cells studies or diagnostics due to benefits such as the reduced sample volume, low cost, portability and the possibility to build new analytical devices or be integrated into conventional ones.
Mariana, Medina-Sánchez +2 more
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IEE Colloquium on Microsensors in Medicine, 1997
Using the example of open-tubular liquid chromatography, the authors demonstrate improved performance, cheap and simple production and miniaturisation through microengineering. Improved performance can result from efficient heat transfer (capillary electrophoresis and PCR), reduced diffusion path lengths (chromatography and coupled chemical reactions ...
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Using the example of open-tubular liquid chromatography, the authors demonstrate improved performance, cheap and simple production and miniaturisation through microengineering. Improved performance can result from efficient heat transfer (capillary electrophoresis and PCR), reduced diffusion path lengths (chromatography and coupled chemical reactions ...
openaire +1 more source
Lab-on-a-chip for drug development
Advanced Drug Delivery Reviews, 2003Significant advances have been made in the development of micro-scale technologies for biomedical and drug discovery applications. The first generation of microfluidics-based analytical devices have been designed and are already functional. Microfluidic devices offer unique advantages in sample handling, reagent mixing, separation, and detection.
Bernhard H, Weigl +2 more
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Lab on a Chip for Live-Cell Manipulation
IEEE Design & Test of Computers, 2007Precisely manipulating and sorting live cells on a lab on a chip is still a major challenge. This article shows how to use dielectrophoresis for cell sorting. The authors also describe a prototype CMOS chip with a sensor-actuator array, row-column addressing logic and readout circuitry.
G. Medoro +4 more
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Lab-on-a-Chip Multiplex Assays
2016Lab-on-a-chip multiplex assays allow a rapid identification of multiple parameters in an automated manner. Here we describe a lab-based preparation followed by a rapid and fully automated DNA microarray hybridization and readout in less than 10 min using the Fraunhofer in vitro diagnostics (ivD) platform to enable rapid identification of bacterial ...
Harald, Peter +2 more
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Lab-on-a-chip: applications in proteomics
Current Opinion in Chemical Biology, 2002Recent advances in chip-based separation of proteins provide methods that are faster and more convenient than conventional gel electrophoresis. Rapid and automated protein sizing on a chip is at the commercial stage and first attempts have been made to perform two-dimensional separation on a chip.
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