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Lab-on-a-Chip Devices for Chemical Analysis
2013[Excerpt] Overview: The healthcare sector is nowadays one of the most dynamic and where novelty is a strategic and operational imperative. The possibility of increasing the quantity and quality of clinical analyses, performed with instantaneous results and outside clinical laboratories, contributes to a better quality in healthcare services and also a ...
Minas, Graça, Catarino, Susana Oliveira
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Lab-on-a-Chip Devices for Chemical Analysis
2008A Lab-on-a-Chip for chemical analysis is a miniaturized device capable of analyzing chemical parameters in fluids. It comprises in a single chip the liquid-handling, the detection and the readout systems. Its reduced size and weight could improve the performance of an analysis and allow the device to be used in mobile chemical analysis equipment, such ...
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Silicon nanophotonic devices for integrated lab-on-a-chip sensing
2010 Annual International Conference of the IEEE Engineering in Medicine and Biology, 2010We present our recent progress in designing nanophotonic devices for integrated sensing applications. We focus on Si-based microresonators and on-chip spectrometers as the main building blocks to implement compact sensing platforms with strong light-matter interaction.
Babak, Momeni +5 more
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High-pressure liquid chromatography in lab-on-a-chip devices
Analytical and Bioanalytical Chemistry, 2007The miniaturization of high-pressure (or high-performance) liquid chromatography (LC) concerning the column inner diameter (i.d.) and volumetric flow rates is an ongoing trend that is mainly driven by the need to handle small volumes of complex sample, e.g., for the elucidation of physiological processes and identification of successful drug candidates,
Steffen, Ehlert, Ulrich, Tallarek
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Multiplexed optical pathogen detection with lab‐on‐a‐chip devices
Journal of Biophotonics, 2009AbstractInfectious diseases are still a main cause of human morbidity and mortality. Advanced diagnostics is considered to be a key driver to improve the respective therapeutic outcome. The main factors influencing the impact of diagnostics include: assay speed, availability, information content, in‐vitro diagnostics and cost, for which molecular ...
Holger, Schulze +3 more
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Chitosan: an integrative biomaterial for lab-on-a-chip devices
Lab on a Chip, 2010Chitosan is a naturally derived polymer with applications in a variety of industrial and biomedical fields. Recently, it has emerged as a promising material for biological functionalization of microelectromechanical systems (bioMEMS). Due to its unique chemical properties and film forming ability, chitosan serves as a matrix for the assembly of ...
S T, Koev +6 more
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Integrated electrochemical DNA biosensors for lab‐on‐a‐chip devices
ELECTROPHORESIS, 2009AbstractAnalytical devices able to perform accurate and fast automatic DNA detection or sequencing procedures have many potential benefits in the biomedical and environmental fields. The conversion of biological or biochemical responses into quantifiable optical, mechanical or electronic signals is achieved by means of biosensors.
Mònica, Mir +2 more
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2017
Microfluidic devices have become a reality in the healthcare sector for the analysis of (bio) chemical parameters and diagnosis applications, due to their small dimensions, accuracy, low cost, low power consumption, and portability. This chapter intends to discuss the main challenges regarding the application of lab-on-a-chip devices for diagnosis ...
Catarino, Susana Oliveira +2 more
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Microfluidic devices have become a reality in the healthcare sector for the analysis of (bio) chemical parameters and diagnosis applications, due to their small dimensions, accuracy, low cost, low power consumption, and portability. This chapter intends to discuss the main challenges regarding the application of lab-on-a-chip devices for diagnosis ...
Catarino, Susana Oliveira +2 more
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Integrated Spectrometers for Lab-on-a-Chip Devices
2013Miniaturization of spectrometers for microfluidic applications is currently an intense area of research. This thesis is devoted to the design, fabrication, and testing of a planar optical microspectrometer. Optical microspectrometers are potentially important candidates for noninvasive detection and identification of cells and other biological material.
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Integrated Fluorescence Sensing for Lab-on-a-chip Devices
2006 IEEE/NLM Life Science Systems and Applications Workshop, 2006A low noise optical sensor and biocompatible microscale optical filters for integrated fluorescence sensors were developed and tested. The sensor was fabricated in a 0.5 µ m CMOS process. The measured reset noise of the sensor is reduced by a factor of 10 compared to conventional active pixel sensors.
Honghao Ji +3 more
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