Results 51 to 60 of about 104,822 (332)

Challenges in lab-on-a-chip technology

Frontiers in Lab on a Chip Technologies, 2022
Lab-on-a-chip technologies, also known as μ-TAS (or micro-total analytical systems), involving the integration of analysis methods into devices and systems, have made significant impacts for over 3 decades, providing methods to analyze real samples, on ...
J. Cooper
semanticscholar   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Lab-on-Chip for Testing Myelotoxic Effect of Drugs and Chemicals [PDF]

, 2014
This paper was presented at the 4th Micro and Nano Flows Conference (MNF2014), which was held at University College, London, UK. The conference was organised by Brunel University and supported by the Italian Union of Thermofluiddynamics, IPEM, the ...
4th Micro and Nano Flows Conference (MNF2014), Bonomi, A, Cavicchini, L, Cocce, V, Fiore, GB, Gazaneo, A, Occhetta, P, Pessina, A, Rasponi, M, Redaelli, A   +9 more
core  

Integration of capillary and EWOD technologies for autonomous and low-power consumption micro-analytical systems [PDF]

, 2016
This work presents a miniaturized system combining, on the same microfluidic chip, capillarity and electrowetting-on-dielectric (EWOD) techniques for movement and control of fluids.
Bellini, Enrica, CAPRINI, DAVIDE, CAPUTO, Domenico, DE CESARE, Giampiero, Llorca, Pablo R., LOVECCHIO, NICOLA, NARDECCHIA, MARCO, NASCETTI, Augusto, PETRUCCI, GIULIA   +8 more
core   +1 more source

Lab-on-a-chip technologies for food safety, processing, and packaging applications: a review

Environmental Chemistry Letters, 2021
The advent of microfluidic systems has led to significant developments in lab-on-a-chip devices integrating several functions onto a single platform.
A. Sridhar, A. Kapoor, Ponnusamy Senthil Kumar, M. Ponnuchamy, Balasubramanian Sivasamy, D. Vo   +5 more
semanticscholar   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Efficient memristor accelerator for transformer self-attention functionality

Scientific Reports
The adoption of transformer networks has experienced a notable surge in various AI applications. However, the increased computational complexity, stemming primarily from the self-attention mechanism, parallels the manner in which convolution operations ...
Meriem Bettayeb, Yasmin Halawani, Muhammad Umair Khan, Hani Saleh, Baker Mohammad   +4 more
doaj   +1 more source

Monitoring Contractile Cardiomyocytes via Impedance Using Multipurpose Thin Film Ruthenium Oxide Electrodes

Sensors, 2021
A ruthenium oxide (RuOx) electrode was used to monitor contractile events of human pluripotent stem cells-derived cardiomyocytes (hPSC-CMs) through electrical impedance spectroscopy (EIS).
Esther Tanumihardja, Douwe S. de Bruijn, Rolf H. Slaats, Wouter Olthuis, Albert van den Berg   +4 more
doaj   +1 more source

Lab-on-a-Chip Platforms as Tools for Drug Screening in Neuropathologies Associated with Blood–Brain Barrier Alterations

Biomolecules, 2021
Lab-on-a-chip (LOC) and organ-on-a-chip (OOC) devices are highly versatile platforms that enable miniaturization and advanced controlled laboratory functions (i.e., microfluidics, advanced optical or electrical recordings, high-throughput screening). The
C. E. Staicu, F. Jipa, E. Axente, M. Radu, B. Radu, F. Sima   +5 more
semanticscholar   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source