Towards photonic biosensing using a three-port mach-zehnder interferometer in a silicon nitride platform [PDF]
, 2018 Integrated photonics enables sensitive and label-free optical biosensors for the detection of chemical and biological substances and is therefore promising for future lab-on-chip solutions.
Fernández-Gavela, Adrián +5 more
core +1 more source
Simulation of magnetic active polymers for versatile microfluidic devices [PDF]
, 2013 We propose to use a compound of magnetic nanoparticles (20-100 nm) embedded in a flexible polymer (Polydimethylsiloxane PDMS) to filter circulating tumor cells (CTCs).
Bance, Simon +9 more
core +1 more source
Oncoimmunology Meets Organs-on-Chip
Frontiers in Molecular Biosciences, 2021 Oncoimmunology represents a biomedical research discipline coined to study the roles of immune system in cancer progression with the aim of discovering novel strategies to arm it against the malignancy.
Fabrizio Mattei +8 more
doaj +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Pectobacterium atrosepticum Biosensor for Monitoring Blackleg and Soft Rot Disease of Potato
Biosensors, 2020 Pectobacterium atrosepticum (Pba) is a quarantine and threatening phytopathogen known as the causal agent of blackleg and soft rot disease of potatoes in many areas.
Mahdis Hashemi Tameh +5 more
doaj +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Fabrication and testing of polydimethylsiloxane (PDMS) microchannel for lab-on-chip (LOC) magnetically-labelled biological cells separation [PDF]
, 2016 Microfluidics channel of micron-to millimeter in dimension has been widely used for fluid handling in transporting, mixing and separating biological cells in Lab-on-Chip (LoC) applications.
Abidin, U., Majlis, B. Y., Yunas, J.
core +1 more source
Compartmentalized 3D Tissue Culture Arrays under Controlled Microfluidic Delivery
Scientific Reports, 2017 We demonstrate an in vitro microfluidic cell culture platform that consists of periodic 3D hydrogel compartments with controllable shapes. The microchip is composed of approximately 500 discontinuous collagen gel compartments locally patterned in between
Burcu Gumuscu +4 more
doaj +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Design and Development of Microfluidic Lab-On-Chip Bioimpedance Analyzer [PDF]
, 2015 Impedance analysis for biological samples has proved to be one of the most powerful non-invasive techniques developed so far, for understanding the electrophysiological properties of the tissues.
Mohanty, Samyak
core