Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
FEBS Open Bio, EarlyView.We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
Genetic identification of three CITES-listed sharks using a paper-based Lab-on-a-Chip (LOC).
PLoS ONEThreatened shark species are caught in large numbers by artisanal and commercial fisheries and traded globally. Monitoring both which shark species are caught and sold in fisheries, and the export of CITES-restricted products, are essential in reducing ...
Guuske P Tiktak +12 more
doaj +1 more source
Real-time Monitoring System of Hazardous Chemicals Based on 6LoWPAN and WLAN
Chemical Engineering Transactions, 2016 To ensure the safe storage and use of lab hazardous chemicals, this paper designs and develops a 6LoWPAN and WLAN-based hazardous chemicals monitoring system.
G.Q. Hu
doaj +1 more source
Lab on Paper Sensor for Explosive Materials Detection
The 9th International Symposium on Sensor Science, 2022 Michal Chudy +8 more
openaire +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
FEBS Open Bio, EarlyView.BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti +5 more
wiley +1 more source
THE RELATIONSHIP BETWEEN SELF-CONFIDENCE AND STUDENTS PERFORMANCE IN BIOLOGY LAB EXCERCISE
EDUSAINS, 2017 Biology lab exercise are an important aspect on learning process. However, the outcome of the lab activity might not come as the curriculum goals expected. It is due to several reasons.
Dina Rahma Fadlilah +2 more
doaj +1 more source
Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank
FEBS Open Bio, EarlyView.Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer +7 more
wiley +1 more source
User-friendly lab-on-paper optical sensor for the rapid detection of bacterial spoilage in packaged meat products. [PDF]
RSC Adv, 2021 Abo Dena AS +4 more
europepmc +1 more source