Results 81 to 90 of about 52,192,158 (333)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Genetic identification of three CITES-listed sharks using a paper-based Lab-on-a-Chip (LOC).

open access: yesPLoS ONE
Threatened shark species are caught in large numbers by artisanal and commercial fisheries and traded globally. Monitoring both which shark species are caught and sold in fisheries, and the export of CITES-restricted products, are essential in reducing ...
Guuske P Tiktak   +12 more
doaj   +1 more source

3D Printed Unibody Lab-on-a-Chip: Features Survey and Check-Valves Integration

open access: yesMicromachines, 2015
The unibody lab-on-a-chip (ULOC) concept entails a fast and affordable micro-prototyping system built around a single monolithic 3D printed element (unibody).
Germán Comina   +2 more
doaj   +1 more source

foldy-lab/Transcriptomics-of-Pvalb-Cells: Paper Submission

open access: yes, 2020
<p>Code used for paper submission</p ...
foldy-lab
core   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

The Experience of Developing the UJAmI Smart Lab

open access: yesIEEE Access, 2018
In the context of ambient-assisted living and monitoring activities and behaviors, the concept of smart homes/environments has emerged as a research and development field with many examples appearing in a range of different contexts (universities ...
M. Espinilla   +3 more
doaj   +1 more source

Lab-On-Fiber Technology: A Roadmap toward Multifunctional Plug and Play Platforms

open access: yesItalian National Conference on Sensors, 2020
This review presents an overview of the “lab-on-fiber technology” vision and the main milestones set in the technological roadmap to achieve the ultimate objective of developing flexible, multifunctional plug and play fiber-optic platforms designed for ...
M. Pisco, A. Cusano
semanticscholar   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

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