Results 61 to 70 of about 4,187,542 (302)

Label‐Free and Immobilization‐Free Protein‐Binding Assays by Ultraviolet Transient Absorption Microscopy

open access: yesAdvanced Science
Protein–ligand interactions are central to understanding biological mechanisms and drug discovery, yet conventional assays often rely on labeling or immobilization that can alter natural binding.
Jianghao Shen   +5 more
doaj   +1 more source

A Label-Free Protein Microfluidic Array for Parallel Immunoassays

open access: yes, 2006
A label-free protein microfluidic array for immunoassays based on the combination of imaging ellipsometry and an integrated microfluidic system is presented.
王战会   +5 more
core   +1 more source

Label-free virtual Hematoxylin and Eosin (H&E) staining using second generation Photoacoustic Remote Sensing (PARS)

open access: yes, 2021
In the past decades, absorption modalities have emerged as powerful tools for label-free functional and structural imaging of cells and tissues. Many biomolecules present unique absorption spectra providing chromophore-specific information on properties ...
Benjamin R. Ecclestone (14384328)   +5 more
core   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Study and development of label-free optical biosensors for biomedical applications [PDF]

open access: yes, 2011
For the majority of assays currently performed, fluorescent or colorimetric chemical labels are commonly attached to the molecules under study so that they may be readily visualized.
Charles J. Choi, Choi, Charles J.
core  

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Label-free sensitive detection of influenza virus using PZT discs with a synthetic sialylglycopolymer receptor layer [PDF]

open access: yesRoyal Society Open Science, 2019
We describe rapid, label-free detection of Influenza A viruses using the first radial mode of oscillations of lead zirconate titanate (PZT) piezoelectric discs with a 2 mm radius and 100 µm thickness fabricated from a piezoelectric membrane.
Alexander S. Erofeev   +5 more
doaj   +1 more source

Label-Free Bioaerosol Sensing Using Mobile Microscopy and Deep Learning

open access: yes, 2018
Conventional bioaerosol sensing requires the sampled aerosols in the field to be transferred to a laboratory for manual inspection, which can be rather costly and slow, also requiring a professional for labeling and microscopic examination of the samples.
Yibo Zhang (288948)   +23 more
core   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Label-Free Biosensors for Cell Biology

open access: yesInternational Journal of Electrochemistry, 2011
Label-free biosensors for studying cell biology have finally come of age. Recent developments have advanced the biosensors from low throughput and high maintenance research tools to high throughput and low maintenance screening platforms.
Ye Fang
doaj   +1 more source

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