Results 21 to 30 of about 440,393 (255)
Label‐free characterization of an extracellular vesicle‐based therapeutic
Journal of Extracellular Vesicles, 2021 Interest in mesenchymal stem cell derived extracellular vesicles (MSC‐EVs) as therapeutic agents has dramatically increased over the last decade. Current approaches to the characterization and quality control of EV‐based therapeutics include particle ...
Eleni Priglinger +12 more
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Label-free receptor assays [PDF]
Drug Discovery Today: Technologies, 2010 Label-free biosensors offer integrated, kinetic and multi-parametric measures of receptor biology and ligand pharmacology in whole cells. Being highly sensitive and pathway-unbiased, label-free receptor assays can be used to probe the systems cell biology including pleiotropic signaling of receptors, and to characterize the functional selectivity and ...
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Metamaterial-based label-free optical biosensing
Cailiao gongcheng, 2021 Metamaterials have drawn extensive attention for their fine regulation of electromagnetic waves at subwavelength scales. They have abundant electromagnetic modes, and support highly confined and enhanced electromagnetic fields on the surface which are ...
TAO Cheng-dong +5 more
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High-throughput, nonperturbing quantification of lipid droplets with digital holographic microscopy
Journal of Lipid Research, 2018 In vitro differentiating adipocytes are sensitive to liquid manipulations and have the tendency to float. Assessing adipocyte differentiation using current microscopy techniques involves cell staining and washing, while using flow cytometry involves cell
Vasco Campos +4 more
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Cancer Informatics, 2008 Recently, several research groups have published methods for the determination of proteomic expression profiling by mass spectrometry without the use of exogenously added stable isotopes or stable isotope dilution theory.
Soyoung Ryu +5 more
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Label-Free Optical Resonator-Based Biosensors
Sensors, 2020 The demand for biosensor technology has grown drastically over the last few decades, mainly in disease diagnosis, drug development, and environmental health and safety.
Donggee Rho +2 more
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Label-Free Sensing of Biorecognition on Liposomes [PDF]
ACS Sensors, 2020 Nanometer-sized liposomes decorated with macromolecules are increasingly used as drug delivery vehicles due to their long lifetimes and target cell specificity, but surface characterization methods often change their properties, which leads to incorrect results. Ligand binding is commonly applied for characterizing these surface modifications. Here, we
Martin K. Rasmussen +2 more
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Label free, quantitative single-cell fate tracking of time-lapse movies
MethodsX, 2019 Historically, the ability to perform multi-day time-lapse imaging of adherent cells required expensive and specialized microscopy equipment. As byproduct of this cost, many labs would synchronize cells using inhibitors such as hydroxyurea and thymidine ...
C. Elizabeth Caldon, Andrew Burgess
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3D structured biochip for label free determinations at the point-of-need
Micro and Nano Engineering, 2022 A novel optical label-free biosensing approach is introduced aiming to remove the current limitations of optical biosensors in their application of on-site food analysis.
G. Zisis +5 more
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Analytical Science Advances, 2020 Surface‐enhanced Raman spectroscopic (SERS) approaches are emerging for bacteria analysis whereby bacteria cells can be measured based on their biochemical composition (label‐free) or with the aid of a chemical label to enhance the SERS signal. Combining
Michael E. Hickey, Siyue Gao, Lili He
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