Results 31 to 40 of about 440,393 (255)
Beyond fluorescence: A critical look at AI-powered brightfield analysis for T-cell killing assays
SLAS DiscoveryThis comment evaluates dela Cruz-Chuh et al.’s AI-based label-free workflow for analyzing T-cell mediated tumor killing via brightfield imaging.
Xiaoman Liu, Zihan Gao, Jiachun Xu
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6. Label-free selective plane illumination microscopy of tissue samples
Journal of the Saudi Heart Association, 2017 Basic Science Research. Presentation type: Poster Presentation. Introduction: There is an increasing demand for non-invasive, label-free, three-dimensional imaging techniques for characterisation of optically turbid samples such as tissue engineered ...
Muteb Alharbi +3 more
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FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
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Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
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, 2023 Label-free quantification is an important mass spectrometry method that requires no specific sample labelingInstead, it utilized MS/MS generated signals of specific peptides for comparison to define protein expression modifications between samples. Two alternative label-free quantification strategies are frequently used.
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Label-Free Liver Tumor Segmentation
2023 IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR), 2023 CVPR ...
Qixin Hu +6 more
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
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Label-Free Ultrasensitive Memristive Aptasensor [PDF]
Nano Letters, 2016 We present the very first worldwide ever-reported electrochemical biosensor based on a memristive effect and DNA aptamers. This novel device is developed to propose a completely new approach in cancer diagnostics. In this study, an affinity-based technique is presented for the detection of the prostate specific antigen (PSA) using DNA aptamers.
Tzouvadaki, Ioulia +6 more
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Label‐free Raman spectroscopy for the assessment of liver fibrosis
MedComm – Future Medicine, 2023 The enormous incidence and dire consequences of liver fibrosis highlight the need for biologically plausible markers as readouts of pathology and drug efficacy.
Huiying Cao +10 more
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
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