Results 131 to 140 of about 3,139,625 (302)

From superior contrast to super resolution label free optical microscopy

npj Imaging
Label-free optical microscopy utilizes the information encoded in light scattered off unlabeled particles to generate the images. This review article starts off with a discussion on how this light matter interaction gives rise to the issues of poor ...
Nikhil Jayakumar, Balpreet Singh Ahluwalia   +1 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Information‐Distilled Generative Label‐Free Morphological Profiling Encodes Cellular Heterogeneity

Advanced Science
Image‐based cytometry faces challenges due to technical variations arising from different experimental batches and conditions, such as differences in instrument configurations or image acquisition protocols, impeding genuine biological interpretation of ...
Michelle C. K. Lo, Dickson M. D. Siu, Kelvin C. M. Lee, Justin S. J. Wong, Maximus C. F. Yeung, Michael K. Y. Hsin, James C. M. Ho, Kevin K. Tsia   +7 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Towards a high-throughput label-free detection system combining localized-surface plasmon resonance and microfluidics

, 2012
This work reports an integrated platform combining localized-surface plasmon resonance (LSPR) and microfluidic chips to carry out multiplexed and label-free protein analysis.
Jianzhong Xi, Xi, Jianzhong, Jiang, Xingyu, Zhang, Yi, Yi Zhang, Hsu, Chuen-Yuan, ChuenYuan Hsu, Lin, Kuan-Jiuh, Yunfang Tang（汤云芳）, YiHeui Hsieh, KuanJiuh Lin, Xingyu Jiang, Tang, Yunfang, Hsieh, Yi-Heui   +13 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Consumer Behaviour towards Own Label: monitoring the Greek experience

In Greece, the traditional perceptions of private label were once of low quality, unbranded alternatives, attracting the most cost-conscious consumers.
Boutsouki, Christina, Masouti, Zafeiria, Zotos, Yorgos   +2 more
core   +1 more source

Label-Free Mass Spectrometry

BioTechniques, 2007
Lynne Lederman
doaj   +1 more source

Fast Label‐Free Metabolic Profile Recognition Identifies Phenylketonuria and Subtypes

Advanced Science
Phenylketonuria (PKU) is the most common inherited metabolic disease in humans. Clinical screening of newborn heel blood samples for PKU is costly and time‐consuming because it requires multiple procedures, like isotope labeling and derivatization, and ...
Haiyang Su, Huiwen Zhang, Jiao Wu, Lin Huang, Mengji Zhang, Wei Xu, Jing Cao, Wanshan Liu, Ning Liu, Hongwei Jiang, Xuefan Gu, Kun Qian   +11 more
doaj   +1 more source