Results 51 to 60 of about 4,185,007 (300)

Label-Free Fluorescence Quantitative Detection Platform on Plasmonic Silica Photonic Crystal Microsphere Array

, 2022
We have demonstrated the proof-of-concept of a label-free fluorescence quantitative detection platform based on gold nanoparticle (AuNP) enhancement intrinsic fluorescence of protein on the silica photonic crystal microsphere (SPCM) array. The label-free
Wei Li (7081), Ruimin Xu (2014156), Jianlin Li (1722952), Shijie Dai (10535196), Xin Wang (91924), Menghua Dou (11447345), Qianjin Li (6054386)   +6 more
core   +1 more source

Provider and Parent Perspectives on Prioritizing the “Asking and Monitoring” Pediatric Cancer Psychosocial Standards of Care

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The Standards for Psychosocial Care for Children with Cancer and Their Families (“Standards”) are evidence‐based guidelines for psychosocial care in pediatric oncology. Care related to the three “Asking and Monitoring” Standards—Assessment of Psychosocial Needs, Assessment of Financial Needs, and Monitoring Neurocognitive Problems ...
Julia B. Tager, Natalie Koskela‐Staples, Emily M. Pariseau, Michele Scialla, Kimberly Buff, Lori Wiener, Victoria Sardi Brown, Anne E. Kazak, Kimberly S. Canter   +8 more
wiley   +1 more source

Label‐free Raman spectroscopy for the assessment of liver fibrosis

MedComm – Future Medicine, 2023
The enormous incidence and dire consequences of liver fibrosis highlight the need for biologically plausible markers as readouts of pathology and drug efficacy.
Huiying Cao, Chen Ma, Zhitao Wu, Lin Sun, Wenjing Liu, Chenhui Ma, Feihong Chen, Zhaoliang Peng, Lijiang Xuan, Ruimin Huang, Guoyu Pan   +10 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

High‐Throughput, Label‐Free and Slide‐Free Histological Imaging by Computational Microscopy and Unsupervised Learning

Advanced Science, 2022
Rapid and high‐resolution histological imaging with minimal tissue preparation has long been a challenging and yet captivating medical pursuit. Here, the authors propose a promising and transformative histological imaging method, termed computational ...
Yan Zhang, Lei Kang, Ivy H. M. Wong, Weixing Dai, Xiufeng Li, Ronald C. K. Chan, Michael K. Y. Hsin, Terence T. W. Wong   +7 more
doaj   +1 more source

Label-free quantification

, 2023
Label-free quantification is an important mass spectrometry method that requires no specific sample labelingInstead, it utilized MS/MS generated signals of specific peptides for comparison to define protein expression modifications between samples. Two alternative label-free quantification strategies are frequently used.
openaire   +2 more sources

Label-free stimulated Raman imaging of foraminifera

, 2017
Label-free stimulated Raman imaging of ...
Golreihan, Asefeh, Johan Vellekoop (7825409), Arne Deprez (830651), Maarten Roeffaers (566054), Fujita, Yasuhiko, Steuwe, Christian, Asefeh Golreihan (8021021), Roeffaers, Maarten, Vellekoop, Johan, Swennen, Rudy, Lineke Woelders (5504390), Woelders, Lineke, Christian Steuwe (1387533), Rudy Swennen (5164064), Yasuhiko Fujita (1596409), Deprez, Arne   +15 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Label-free volumetric histopathology of thick-tissue slides - neuroendorine tumor

, 2020
Label-free volumetric histopathology of thick-tissue slides - neuroendorine ...
yongkeun park (8695308)
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source