Results 111 to 120 of about 4,187,542 (302)
Label-Free Quantitation for Clinical Proteomics
, 2016 Label-free quantification (LFQ) has emerged as a viable option for quantitative LC-MS/MS-based proteomic analyses for use on the scale of hundreds of samples such as are encountered in clinical analysis. Notably, sample preparation, sample loading, HPLC separations, and mass spectrometric performance must be highly reproducible for this approach to be ...
Robert Moulder +2 more
openaire +3 more sources
Label-free volumetric histopathology of thick-tissue slides - PanIN, low grade
, 2020 Label-free volumetric histopathology of thick-tissue slides - PanIN, low ...
yongkeun park (8695308)
core +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
High Quality–Factor All–Dielectric Metacavity for Label–Free Biosensing
Advanced ScienceHigh sensitivity and high quality‐factor are crucial for achieving outstanding sensing performance in photonic biosensors. However, strong optical field confinement and high light–biomolecule interactions on photonic surfaces are usually contradictory ...
Yuqiao Zheng +12 more
doaj +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Label-free volumetric histopathology of thick-tissue slides - intraductal papillary neoplasm
, 2020 Label-free volumetric histopathology of thick-tissue slides - intraductal papillary ...
yongkeun park (8695308)
core +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Quality Perceptions of Private Label Brands: Conceptual Framework and Agenda for Research [PDF]
Private Label brands had seen an impressive growth in past few decades. Though, initially private label brands had a low-priced strategy, retailers made efforts for serious quality improvements in recent years. However, they have continued to suffer from
Koshy, Abraham, Abhishek
core
Label-free multiphoton microscopy: Much more than fancy images
, 2021 © 2021 by the authors. Licensee MDPI, Basel, Switzerland. Multiphoton microscopy has recently passed the milestone of its first 30 years of activity in biomedical research.
D Sandrin (10576958) +4 more
core