Results 251 to 260 of about 4,187,542 (302)

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Subcellular nanoparticle trafficking investigated with label-free, live cell imaging. [PDF]

Nanoscale Horiz
Nelson EB, Covarrubias G, Nabar N, Gomerdinger VF, Scott A, Hammond PT, Straehla JP.   +6 more
europepmc   +1 more source

Exploratory Label-Free Proteomic Profiling of the <i>Escherichia coli</i> Response to Sub-Inhibitory CORM-3 Exposure. [PDF]

Microorganisms
Ali S, Dimonte S, Aquaro S, Babakir-Mina M, Di Bonaventura G, Pompilio A.   +5 more
europepmc   +1 more source

Label-Free Target Discovery Strategy for Natural Active Products. [PDF]

Biomolecules
Shan L, Chen Y, Cao X, Jin X, Liu B.
europepmc   +1 more source

Portable Raman spectroscopy combined with machine learning for rapid and label-free recognition of five pathogenic bacteria. [PDF]

Front Microbiol
Cao S, Pang R, Chen Y, Zhong L, Dong X, Li H, Yin H.   +6 more
europepmc   +1 more source

Label-free optical observation of disordered-to-ordered transitions in single intrinsically disordered proteins. [PDF]

NPJ Biosens
Zargarbashi S, Dominguez C, Peters M, Yousefi A, Munday S, Wang Y, Chatterjee S, Hudson AJ, Gordon R, Mellor CJ, Xu L, Rahmani M, Ying C.   +12 more
europepmc   +1 more source

Discrimination of Closely Related <i>Vibrio</i> Strains by Label-Free Surface-Enhanced Raman Spectroscopy (SERS). [PDF]

Biology (Basel)
Mazlan AN, Leong N, Christianus A, Zan Z, Ariffin N, Xie J, Yong ASK, Chong CM.   +7 more
europepmc   +1 more source

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Label-free cell profiling

Analytical Biochemistry, 2013
A surface plasmon resonance (SPR) array imaging method is outlined for label-free cell profiling. Red blood cells (RBCs) were injected into a flow chamber on top of a spotted sensor surface. Spots contained antibodies to various RBC membrane antigens. A typical sensorgram showed an initial response corresponding to cell sedimentation (S) followed by a ...
Schasfoort, Richard B. M., Bentlage, Arthur E. H., Stojanovic, Ivan, van der Kooi, Alex, van der Schoot, Ellen, Terstappen, Leon W. M. M., Vidarsson, Gestur   +6 more
openaire   +3 more sources

Recent advances in label-free detection in vitro and label-free imaging in vivo

Coordination Chemistry Reviews
Chun-Yang Zhang
exaly   +2 more sources