Results 21 to 30 of about 426,175 (256)
High-throughput, nonperturbing quantification of lipid droplets with digital holographic microscopy
Journal of Lipid Research, 2018 In vitro differentiating adipocytes are sensitive to liquid manipulations and have the tendency to float. Assessing adipocyte differentiation using current microscopy techniques involves cell staining and washing, while using flow cytometry involves cell
Vasco Campos +4 more
doaj +1 more source
Label-free photoacoustic ophthalmic angiography [PDF]
Optics Letters, 2009 We present label-free functional photoacoustic imaging of the ocular microvasculature in living animals. The anterior segment of an adult mouse was imaged with a laser exposure level well within the American National Standards Institute safety standards.
Hu, Song +3 more
openaire +3 more sources
Label-Free Optical Resonator-Based Biosensors
Sensors, 2020 The demand for biosensor technology has grown drastically over the last few decades, mainly in disease diagnosis, drug development, and environmental health and safety.
Donggee Rho +2 more
doaj +1 more source
Cancer Informatics, 2008 Recently, several research groups have published methods for the determination of proteomic expression profiling by mass spectrometry without the use of exogenously added stable isotopes or stable isotope dilution theory.
Young Ah Goo +5 more
doaj +2 more sources
Label free, quantitative single-cell fate tracking of time-lapse movies
MethodsX, 2019 Historically, the ability to perform multi-day time-lapse imaging of adherent cells required expensive and specialized microscopy equipment. As byproduct of this cost, many labs would synchronize cells using inhibitors such as hydroxyurea and thymidine ...
C. Elizabeth Caldon, Andrew Burgess
doaj +1 more source
3D structured biochip for label free determinations at the point-of-need
Micro and Nano Engineering, 2022 A novel optical label-free biosensing approach is introduced aiming to remove the current limitations of optical biosensors in their application of on-site food analysis.
G. Zisis +5 more
doaj +1 more source
Label-Free Ultrasensitive Memristive Aptasensor [PDF]
Nano Letters, 2016 We present the very first worldwide ever-reported electrochemical biosensor based on a memristive effect and DNA aptamers. This novel device is developed to propose a completely new approach in cancer diagnostics. In this study, an affinity-based technique is presented for the detection of the prostate specific antigen (PSA) using DNA aptamers.
Tzouvadaki, Ioulia +6 more
openaire +3 more sources
Analytical Science Advances, 2020 Surface‐enhanced Raman spectroscopic (SERS) approaches are emerging for bacteria analysis whereby bacteria cells can be measured based on their biochemical composition (label‐free) or with the aid of a chemical label to enhance the SERS signal. Combining
Michael E. Hickey, Siyue Gao, Lili He
doaj +1 more source
, 2023 Label-free quantification is an important mass spectrometry method that requires no specific sample labelingInstead, it utilized MS/MS generated signals of specific peptides for comparison to define protein expression modifications between samples. Two alternative label-free quantification strategies are frequently used.
openaire +1 more source
Biopatterning for label-free detection [PDF]
Colloids and Surfaces B: Biointerfaces, 2010 We present a biopatterning technique suitable for applications which demand a high degree of surface cleanliness, such as immobilization of biological recognition elements onto label-free biosensors. In the case of label-free biosensing, the mechanism of signal transduction is based on surface bound matter, making them highly sensitive to surface ...
Julie M, Goddard +4 more
openaire +2 more sources