Results 41 to 50 of about 3,139,625 (302)
, 2022 We have demonstrated the proof-of-concept of a label-free fluorescence quantitative detection platform based on gold nanoparticle (AuNP) enhancement intrinsic fluorescence of protein on the silica photonic crystal microsphere (SPCM) array. The label-free
Wei Li (7081) +6 more
core +1 more source
Beyond fluorescence: A critical look at AI-powered brightfield analysis for T-cell killing assays
SLAS DiscoveryThis comment evaluates dela Cruz-Chuh et al.’s AI-based label-free workflow for analyzing T-cell mediated tumor killing via brightfield imaging.
Xiaoman Liu, Zihan Gao, Jiachun Xu
doaj +1 more source
6. Label-free selective plane illumination microscopy of tissue samples
Journal of the Saudi Heart Association, 2017 Basic Science Research. Presentation type: Poster Presentation. Introduction: There is an increasing demand for non-invasive, label-free, three-dimensional imaging techniques for characterisation of optically turbid samples such as tissue engineered ...
Muteb Alharbi +3 more
doaj +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Label-free stimulated Raman imaging of foraminifera
, 2017 Label-free stimulated Raman imaging of ...
Golreihan, Asefeh +15 more
core +1 more source
Real-time label-free biosensing with integrated planar waveguide ring resonators [PDF]
, 2010 We review the use of planar integrated optical waveguide ring resonators for label free bio-sensing and present recent results from two European biosensor collaborations: SABIO and InTopSens. Planar waveguide ring resonators are attractive for label-free
Sohlström, Hans +2 more
core +1 more source
Label‐free Raman spectroscopy for the assessment of liver fibrosis
MedComm – Future Medicine, 2023 The enormous incidence and dire consequences of liver fibrosis highlight the need for biologically plausible markers as readouts of pathology and drug efficacy.
Huiying Cao +10 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source